Create Account | Sign In: Author or Forum

News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    



Category: Cardiology | Family Medicine | Geriatrics | Internal Medicine | Neurology | Nursing | Journal

Back to Journal Articles

Exercise Cuts Cognitive Deficit Risk for At-Risk Seniors

Last Updated: November 02, 2012.


Older people with white matter changes living independently have lower risk of dementia

Share |

Comments: (0)



For older people with white matter changes living independently, physical activity lowers the risk of cognitive impairment, according to a study published online Nov. 1 in Stroke.

FRIDAY, Nov. 2 (HealthDay News) -- For older people with white matter changes living independently, physical activity lowers the risk of cognitive impairment, according to a study published online Nov. 1 in Stroke.

Ana Verdelho, M.D., from the University of Lisbon in Portugal, and colleagues evaluated prospective data from the 639 participants of the LADIS (Leukoaraiosis and Disability) multinational European study to examine whether physical activity interferes with progression for cognitive impairment and dementia. Participants (74.1 ± 5 years; 55 percent women; 64 percent physically active) were evaluated yearly over three years with a comprehensive clinical protocol and cognitive assessment. Magnetic resonance imaging was performed at baseline and at the study's conclusion.

The researchers found that 90 patients had dementia at the end of follow-up (54 with vascular dementia; 34 with Alzheimer's disease with vascular component; and two with frontotemporal dementia), and 147 had cognitive impairment which was not dementia. Physical activity correlated significantly with reductions in the risk of cognitive impairment (hazard ratio [HR], 0.64), dementia (HR, 0.61), and vascular dementia (HR, 0.42). The associations were independent of other factors, including age, education, severity of white matter change, medial temporal atrophy, previous and incident stroke, and diabetes.

"Our data support the conviction that older subjects with vascular risk factors and evidence for vascular cerebral damage benefit from regular physical activity," the authors write. "We think that [the] relation between physical activity and cognitive impairment should be further studied by interventional studies."

Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.

Previous: Drug Combo Active in Breast Cancer With Brain Metastases Next: Teriparatide Ups Bone Union for Women With Osteoporosis

Reader comments on this article are listed below. Review our comments policy.

Submit your opinion:





Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application


 advertisement.gif (61x7 -- 0 bytes)



Useful Sites
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.