Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Orthopedics | Pharmacy | Journal

Back to Journal Articles

Teriparatide Ups Bone Union for Women With Osteoporosis

Last Updated: November 02, 2012.

 

Teriparatide more effective than bisphosphonate after instrumented lumbar posterolateral fusion

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Injections of teriparatide are more effective than oral bisphosphonate for bone union after instrumented lumbar posterolateral fusion in women with postmenopausal osteoporosis, according to a study published in the Nov. 1 issue of Spine.

FRIDAY, Nov. 2 (HealthDay News) -- Injections of teriparatide are more effective than oral bisphosphonate for bone union after instrumented lumbar posterolateral fusion in women with postmenopausal osteoporosis, according to a study published in the Nov. 1 issue of Spine.

Seiji Ohtori, M.D., Ph.D., from Chiba University in Japan, and colleagues examined the clinical efficacy of teriparatide for bone union in 57 women with osteoporosis diagnosed with degenerative spondylolisthesis who underwent decompression and one- or two-level instrumented posterolateral fusion with a local bone graft. Patients were divided into a teriparatide treatment group (29 patients receiving daily subcutaneous injection of 20 µg teriparatide) or bisphosphonate group (28 women receiving weekly oral administration of 17.5 mg of risedronate).

The researchers found that pain scores improved after surgery but that there were no significant between-group differences. In the teriparatide group, the rate of bone union was 82 percent, compared with 68 percent in the bisphosphonate group, and the average duration of bone union was eight and 10 months, respectively. Both the rate of bone union and average duration of bone union were significantly superior in the teriparatide group versus the bisphosphonate group.

"The teriparatide-treated patients showed superior results in the rate of bone union and average duration of bone union compared with the bisphosphonate-treated patients," the authors write. "We think that teriparatide can enhance spinal fusion in patients with osteoporosis."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2012 HealthDay. All rights reserved.


Previous: Exercise Cuts Cognitive Deficit Risk for At-Risk Seniors Next: Short Sleep Duration Found Not to Lead to Insulin Resistance

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.