Create Account | Sign In: Author or Forum

 
 
News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter    
 

 Headlines:

 

Category: Cardiology | Endocrinology | Family Medicine | Gynecology | Internal Medicine | Critical Care | Emergency Medicine | Nursing | Pathology | Pulmonology | Journal

Back to Journal Articles

Antihypertensive Drugs Also Benefit Non-Hypertensives

Last Updated: May 20, 2009.

 

Meta-analysis shows that treatment reduces heart attacks and stroke regardless of blood pressure

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
In everyone at risk for heart attack or stroke -- including those with normal blood pressure -- antihypertensive treatment significantly reduces the risk of coronary heart disease events and stroke, according to a study published online May 19 in BMJ.

WEDNESDAY, May 20 (HealthDay News) -- In everyone at risk for heart attack or stroke -- including those with normal blood pressure -- antihypertensive treatment significantly reduces the risk of coronary heart disease events and stroke, according to a study published online May 19 in BMJ.

M. R. Law, of Queen Mary University in London, and colleagues conducted a meta-analysis of 108 studies, in which patients were randomized to receive either an antihypertensive drug or placebo, and 46 drug-comparison studies that included a total of 464,000 participants.

In all patients -- including those with and without vascular disease or hypertension -- the researchers found that the use of any of the main classes of antihypertensive drugs which decreased systolic blood pressure by 10 mm Hg or diastolic blood pressure by 5 mm Hg was associated with about a 25 and 33 percent reduced risk of fatal or nonfatal coronary heart disease events and stroke, respectively, and was not associated with an increase in non-vascular mortality. They also found that antihypertensive treatment reduced the risk of heart failure by about 25 percent.

"Perhaps the most controversial aspect of their analysis is their comparison of combination blood pressure therapy at half standard doses with combination therapy at standard dose," states the author of an accompanying editorial. "These findings provide tacit support for the use of a 'polypill' to lower the risk of cardiovascular disease in people likely to be at high risk (such as all people over the age of 55) without first checking their blood pressure."

Two of the authors hold patents (granted and pending) on the formulation of a combined pill to simultaneously reduce four cardiovascular risk factors, including blood pressure.

Abstract
Full Text
Editorial

Copyright © 2009 ScoutNews, LLC. All rights reserved.


Previous: Door-to-Balloon Delays Increase Risk of Death Next: Pain Management May Be Best Option for Critically Ill

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.