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Category: Family Medicine | Monthly Briefing

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June 2009 Briefing - Family Practice

Last Updated: July 01, 2009.

 

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Here are what the editors at HealthDay consider to be the most important developments in Family Practice for June 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA Panel Urging Reduced Acetaminophen Dosing

TUESDAY, June 30 (HealthDay News) -- A panel of U.S. health advisors has recommended changes in the dosing and availability of over-the-counter and prescription acetaminophen due to risks of severe liver damage or death. The recommendations follow a report issued by the U.S. Food and Drug Administration (FDA) last month.

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C-Reactive Protein Not Linked to Cardiovascular Disease Risk

TUESDAY, June 30 (HealthDay News) -- Plasma levels of C-reactive protein (CRP) do not appear to predict coronary heart disease risk, nor cardiovascular disease risk generally, according to a pair of studies in the July 1 issue of the Journal of the American Medical Association.

Abstract - Melander
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Abstract - Elliott
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Protein May Have a Role Supporting Cancer Cells

TUESDAY, June 30 (HealthDay News) -- A protein previously thought only to regulate gene expression in the cell nucleus during an immune response, also exists in the cell mitochondria where it may play a fundamental role converting normal cells to cancer cells, according to a study in the June 26 issue of Science.

Abstract
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Computer-Aided System Detects Missed Lung Cancer

TUESDAY, June 30 (HealthDay News) -- In lung cancer patients, a computer-aided detection system may detect nodules in chest radiography that were initially overlooked by a radiologist, according to a study published in the July issue of Radiology.

Abstract
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Dads' Depression Linked to Later Infant Crying

TUESDAY, June 30 (HealthDay News) -- Symptoms of depression in soon-to-be fathers during pregnancy may be a risk factor for excessive infant crying, according to research published in the July issue of Pediatrics.

Abstract
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Depression Linked to Poor Outcomes in Heart Patients

TUESDAY, June 30 (HealthDay News) -- In heart patients, depression is significantly associated with an increased risk of angina and cardiovascular mortality, according to two studies published online June 29 in Circulation.

Abstract - Arnold
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Abstract - Frasure-Smith
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White-Coat, Masked Hypertension Are Risk Factors

TUESDAY, June 30 (HealthDay News) -- Patients with white-coat hypertension and masked hypertension may have a long-term risk of developing sustained hypertension, according to a study published online June 29 in Hypertension.

Abstract
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Oncology Best Supportive Care Studies Faulted

TUESDAY, June 30 (HealthDay News) -- In oncology, best supportive care studies exhibit ethical and methodological shortcomings, and systematic bias or error that may be due to ad hoc supportive care and lack of standardized delivery, according to a study published online June 29 in the Journal of Clinical Oncology.

Abstract
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Interferon Gamma-1b No Help to Pulmonary Fibrosis Patients

TUESDAY, June 30 (HealthDay News) -- Treating idiopathic pulmonary fibrosis patients with interferon gamma-1b does not improve their chances of survival, according to a study published online June 30 in The Lancet.

Abstract
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Survival Good in Transplant for Congenital Heart Disease

TUESDAY, June 30 (HealthDay News) -- In heart transplant patients, those who are transplanted for congenital heart disease and survive the early postoperative period are usually as likely as other patients to experience late survival, according to a study published in the July 7 issue of the Journal of the American College of Cardiology.

Abstract
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Intense Surveillance Beneficial in Early-Stage Colon Cancer

TUESDAY, June 30 (HealthDay News) -- In patients with stage I and IIA colon cancer, intensive postoperative surveillance is as beneficial as it is in late-stage patients, according to a study published online June 29 in the Journal of Clinical Oncology.

Abstract
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Tiny Dose of Carbon Monoxide Can Damage Fetal Brain

TUESDAY, June 30 (HealthDay News) -- Exposure to even minute levels of carbon monoxide can cause oxidative stress in fetal brain tissue, according to a May 27 study published in BMC Neuroscience.

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Adolescents' Lifespan Belief Linked to Health Outcomes

TUESDAY, June 30 (HealthDay News) -- A perceived risk of early death appears to have a reciprocal relationship with health outcomes and risk behaviors in adolescents, according to research published in the July issue of Pediatrics.

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Swine Flu May Be More Severe in Younger Populations

MONDAY, June 29 (HealthDay News) -- Apparently, healthy young and middle-aged people may be especially susceptible to the swine flu pandemic, according to two studies published online June 29 in the New England Journal of Medicine.

Abstract - Chowell
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Abstract - Perez-Padilla
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Perspective

Knee Replacement Increases Functional Status

MONDAY, June 29 (HealthDay News) -- In elderly patients with knee osteoarthritis, those who undergo total knee arthroplasty have significantly improved functional outcomes compared to those who forgo the surgery, according to a study published in the July issue of Medical Care.

Abstract
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Back-and-Forth Talk Good for Children's Language Skills

MONDAY, June 29 (HealthDay News) -- Talking with small children, not just to them, may be particularly important for healthy language development, according to research published in the July issue of Pediatrics.

Abstract
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Standardized Asthma Terms and End Points Issued

MONDAY, June 29 (HealthDay News) -- The American Thoracic Society (ATS) and European Respiratory Society (ERS) have issued a comprehensive series of recommendations to standardize asthma definitions and end points for use in clinical trials and practice. The recommendations are published in the July 1 issue of the American Journal of Respiratory and Critical Care Medicine.

Abstract
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Golimumab May Be Beneficial for Rheumatoid Arthritis

MONDAY, June 29 (HealthDay News) -- In rheumatoid arthritis patients who have previously received at least one tumor necrosis factor alpha (TNFα) inhibitor, treatment with the new TNFα inhibitor golimumab may significantly reduce signs and symptoms of the disease, according to a study published online June 29 in The Lancet.

Abstract
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Study Highlights Autism's Genetic Complexity

MONDAY, June 29 (HealthDay News) -- A study comparing genetic samples of autistic and normal children has identified 27 different genetic regions where missing or extra copies of DNA segments may interfere with gene function and impair neurological development, according to a study in the June 26 issue of PloS Genetics.

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Melatonin Fails to Relieve Surgery Anxiety in Children

MONDAY, June 29 (HealthDay News) -- Despite positive results treating preoperative anxiety in adults, oral melatonin is not effective in reducing preoperative anxiety in children, according to a study in the July issue of Anesthesiology.

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Plasma Enzyme Essential for Successful Reproduction

MONDAY, June 29 (HealthDay News) -- The plasma enzyme phospholipase C-β1 may be essential for reproduction, according to a study published in the July issue of Endocrinology.

Abstract
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Some Asian Nations Need to Do More to Combat Measles

MONDAY, June 29 (HealthDay News) -- China and Japan must do more to combat measles if the World Health Organization's Western Pacific Region is to meet its target of regional measles elimination by 2012, according to an article published in the June 26 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Many Teens, Adults Not Aware They Have HIV

FRIDAY, June 26 (HealthDay News) -- A high proportion of HIV patients receive an AIDS diagnosis quickly because their HIV was caught late, and many HIV-infected teens and young adults are undiagnosed, according to two studies from the U.S. Centers for Disease Control and Prevention's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention in Atlanta, published in the CDC's June 26 Morbidity and Mortality Weekly Report.

Full Text - Shouse
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Age, Education Affect Post-Sick Leave Transition to Disability

FRIDAY, June 26 (HealthDay News) -- In adults with musculoskeletal disorders who had a lengthy sickness-related work absence, their age, diagnosis, and socioeconomic factors predicted their transition to disability pension in following years, according to research published in the June 15 issue of Spine.

Abstract
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Binge Drinking Associated With Stroke in Korean Men

FRIDAY, June 26 (HealthDay News) -- Korean men who frequently binge drink may face a higher risk of mortality from stroke, particularly hemorrhagic stroke, according to research published online June 25 in Stroke.

Abstract
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Functional Status Declines Over Time After First Stroke

FRIDAY, June 26 (HealthDay News) -- In the five years following a first stroke, patients have modest declines in functional status, which are more noticeable in those with Medicaid or who are uninsured, according to research published online June 25 in Stroke.

Abstract
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Alcohol Causes Most Deaths in Russian Adults Under 55

FRIDAY, June 26 (HealthDay News) -- In many years, alcohol causes more than half of all deaths in the 15 to 54 years age group in Russia, and together with smoking accounts for the large discrepancy in adult mortality between western European countries and Russia, according to a study in the June 27 The Lancet, which has a special focus on alcohol.

Abstract
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Editorial (subscription or payment may be required)

DHA, EPA, Low Glycemic Index Help in Macular Degeneration

THURSDAY, June 25 (HealthDay News) -- Diets that contain more omega-3 fatty acids and have a lower glycemic index may help prevent progression to advanced age-related macular degeneration (AMD), according to research published online June 12 in the British Journal of Ophthalmology.

Abstract
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Drug Combination Found Effective for Sleeping Sickness

THURSDAY, June 25 (HealthDay News) -- In the treatment of sleeping sickness, nifurtimox-eflornithine combination therapy is as effective as eflornithine monotherapy, has a better safety profile, and is suitable for first-line use in control programs in sub-Saharan Africa, according to a study published online June 25 in The Lancet.

Abstract
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Ablative Therapy Cost Effective in Barrett's Esophagus

THURSDAY, June 25 (HealthDay News) -- In patients with Barrett's esophagus, endoscopic ablation is a cost-effective strategy for managing those with high-grade dysplasia, and may also be cost effective for those with low-grade dysplasia or no dysplasia, according to a study published in the June issue of Gastroenterology.

Abstract
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Prenatal Phthalate Exposure Linked to Low Birth Weight

THURSDAY, June 25 (HealthDay News) -- Prenatal exposure to phthalates, a common chemical ingredient in cosmetics and personal care products, increases the risk of an infant being born with low birth weight (LBW), according to a study published online June 25 in the Journal of Pediatrics.

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Depression May Reactivate Inflammatory Bowel Disease

THURSDAY, June 25 (HealthDay News) -- In patients with quiescent inflammatory bowel disease, depression may reactivate inflammation, according to an animal study published in the June issue of Gastroenterology.

Abstract
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Licorice Gargle Can Cut Postoperative Sore Throat

THURSDAY, June 25 (HealthDay News) -- A licorice gargle just before induction of anesthesia may reduce sore throat after surgery, according to research published in the July issue of Anesthesia & Analgesia.

Abstract
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Spinal Cord Stimulation Viable in Deployed Military Personnel

THURSDAY, June 25 (HealthDay News) -- Spinal cord stimulation (SCS) may be a viable approach to treating military personnel with chronic pain who wish to continue overseas deployments, according to research published in the July issue of Anesthesia & Analgesia.

Abstract
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Anxious Heart Attack Patients Struggle to Change Habits

THURSDAY June 25 (HealthDay News) -- Myocardial infarction patients are less likely to adhere to risk-reducing recommendations if they suffer from anxiety, according to a study published in the June 15 issue of the American Journal of Cardiology.

Abstract
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Flu Vaccine Underutilized in Adults With Asthma

THURSDAY, June 25 (HealthDay News) -- Influenza vaccination coverage among adults with asthma 18 to 64 years of age falls short of national objectives, according to research to be published in the August issue of the American Journal of Preventive Medicine.

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Migraine Associated With Cardiovascular Risk in Women

THURSDAY, June 25 (HealthDay News) -- Women who have migraine headaches with aura are at elevated risk for having cardiovascular disease, according to a study published online June 24 in Neurology.

Abstract
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Treating More Patients Cuts Heart Disease Deaths

THURSDAY, June 25 (HealthDay News) -- Increasing the number of coronary heart disease patients treated to 60 percent could save 135,000 additional lives, according to a study published in the June 15 issue of the American Journal of Cardiology.

Abstract
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Very Low Carb Diet Can Treat Irritable Bowel Syndrome

THURSDAY, June 25 (HealthDay News) -- Patients with diarrhea-predominant irritable bowel syndrome who adhere to a very low carbohydrate diet experience relief of symptoms and improved quality of life, according to an article published in the June issue of Clinical Gastroenterology and Hepatology.

Abstract
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Routine Early Angioplasty Benefits High-Risk Patients

WEDNESDAY, June 24 (HealthDay News) -- In patients with a myocardial infarction with ST-segment elevation, routine early angioplasty after fibrinolysis is associated with significantly better outcomes than standard treatment, according to a study in the June 25 issue of the New England Journal of Medicine.

Abstract
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Cranial Irradiation in Pediatric Leukemia Unnecessary

WEDNESDAY, June 24 (HealthDay News) -- In children newly diagnosed with acute lymphoblastic leukemia, effective risk-adjusted chemotherapy may eliminate the need for prophylactic cranial irradiation, according to a study published in the June 25 issue of the New England Journal of Medicine.

Abstract
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Urine Biomarkers Discovered for Acute Appendicitis

WEDNESDAY, June 24 (HealthDay News) -- The presence of certain protein biomarkers in the urine may be useful in the diagnosis of acute appendicitis, which can present with varied symptoms, according to a study reported online June 24 in the Annals of Emergency Medicine.

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Math Model May Lead to Better Tuberculosis Treatment

WEDNESDAY, June 24 (HealthDay News) -- Manipulating the "switching time" when the immune system activates its most powerful cells against airborne pathogens may lead to more effective treatments for tuberculosis, according to a study published online June 22 in the Proceedings of the National Academy of Sciences.

Abstract
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Biomarkers May Be Useful in Predicting Cediranib Response

WEDNESDAY, June 24 (HealthDay News) -- Biomarkers of vascular normalization may be helpful in predicting the response of glioblastoma patients to cediranib treatment, according to research published online June 23 in Cancer Research.

Abstract
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Dual Drug Therapy Found Effective in Prostate Cancer

WEDNESDAY, June 24 (HealthDay News) -- In a phase II clinical trial, treatment with docetaxel and capecitabine dramatically reduced prostate-specific antigen (PSA) levels in a cohort of patients with metastatic, castrate-resistant prostate cancer (CRPC), according to a report in the July issue of the Journal of Urology.

Abstract
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Implanted Device Effective for Mitral Regurgitation

WEDNESDAY, June 24 (HealthDay News) -- A novel coronary sinus mitral repair implant device -- PTMA® -- is feasible and safe in patients with functional mitral regurgitation, according to a study published online June 23 in Circulation: Cardiovascular Interventions.

Abstract
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Cardiac Rehabilitation Is Beneficial for Seniors

WEDNESDAY, June 24 (HealthDay News) -- In older coronary patients, survival is significantly greater in those who attend multiple cardiac rehabilitation sessions, according to a study published in the June 30 issue of the Journal of the American College of Cardiology.

Abstract
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Editorial (subscription or payment may be required)

Americans Paying for More of Their Health Care Costs

WEDNESDAY, June 24 (HealthDay News) -- Out-of-pocket costs are rising for Americans with health care coverage, including premiums, deductibles and copayments, according to a new June 23 report from the U.S. Department of Health & Human Services.

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Copeptin Measurements May Help Rule Out Heart Attack

WEDNESDAY, June 24 (HealthDay News) -- In patients presenting with suspected acute myocardial infarction, combined measurements of copeptin and troponin T may allow for a rapid rule out of the condition, according to a study published in the June 30 issue of the Journal of the American College of Cardiology.

Abstract
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Bariatric Surgery Trims Cancer Incidence in Obese Women

WEDNESDAY, June 24 (HealthDay News) -- Weight loss resulting from bariatric surgery can cut cancer incidence in obese women, but has no significant effect in obese men, according to a study published online June 24 in The Lancet Oncology.

Abstract
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Monitoring May Be Unnecessary After Bisphosphonate Treatment

WEDNESDAY, June 24 (HealthDay News) -- Postmenopausal women treated with a potent bisphosphonate should not undergo bone mineral density monitoring within the first three years of starting treatment because such tests can give misleading results, according to a study published online on June 23 in BMJ.

Abstract
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Elements of Mediterranean Diet Add Up to Lower Mortality

WEDNESDAY, June 24 (HealthDay News) -- Different elements of the Mediterranean diet contribute to its beneficial effect on overall mortality, according to a study published online on June 23 in BMJ.

Abstract
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Antibiotic Prescribing for Acute Cough Varies Widely

WEDNESDAY, June 24 (HealthDay News) -- Antibiotic prescribing patterns for acute cough vary widely, with no discernable difference in patients' recovery, according to a study published online on June 23 in BMJ.

Abstract
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First-Degree Atrioventricular Block Shows Heightened Risk

TUESDAY, June 23 (HealthDay News) -- Patients with first-degree atrioventricular block may have an increased risk of atrial fibrillation, pacemaker implantation, and all-cause mortality, according to a study published in the June 24 issue of the Journal of the American Medical Association.

Abstract
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Midlife Migraine Linked to Brain Infarcts in Older Age

TUESDAY, June 23 (HealthDay News) -- Middle-aged women who have migraine with aura may be more likely than women without headaches to show cerebellar infarct-like lesions on MRI later in life, according to a study in the June 24 Journal of the American Medical Association.

Abstract
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Editorial

Body Mass Index Affects Pancreatic Cancer Risks

TUESDAY, June 23 (HealthDay News) -- Younger adults who are overweight or obese have an increased risk of developing pancreatic cancer and at an earlier age, and older adults who are obese and develop pancreatic cancer have reduced overall survival, according to a study published in the June 24 issue of the Journal of the American Medical Association.

Abstract
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Secondary Causes for Low Bone Mineral Density Common

TUESDAY, June 23 (HealthDay News) -- Many postmenopausal breast cancer survivors may have secondary causes of low bone mineral density that are potentially treatable, according to research published online on June 22 in the Journal of Clinical Oncology.

Abstract
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Vaginal Brachytherapy After Surgery May Offer Benefits

TUESDAY, June 23 (HealthDay News) -- Vaginal brachytherapy may provide improved quality-of-life benefits compared with external-beam radiotherapy following endometrial carcinoma surgery, according to research published online June 22 in the Journal of Clinical Oncology.

Abstract
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Strategies May Improve Outcomes for Rare Tumors

TUESDAY, June 23 (HealthDay News) -- In women with placental-site trophoblastic tumors, stage-adapted management initiated within 48 months after the antecedent pregnancy is associated with improved overall survival and recurrence-free survival, according to a study published online June 23 in The Lancet.

Abstract
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Lipid Control Improved Worldwide Over Past Decade

TUESDAY, June 23 (HealthDay News) -- Control of low-density lipid cholesterol (LDL-C) has improved around the world in the past decade, but almost a third of patients still do not achieve optimal LDL levels, according to a study published online June 22 in Circulation.

Abstract
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Editorial (subscription or payment may be required)

Good Outcomes Seen After Bypass for Kawasaki Disease

TUESDAY, June 23 (HealthDay News) -- In pediatric patients who undergo coronary artery bypass surgery for Kawasaki disease, long-term survival is excellent and subsequent cardiac events can be successfully managed, according to a study published online June 22 in Circulation.

Abstract
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Angiography May Predict Acute Coronary Syndrome

TUESDAY, June 23 (HealthDay News) -- In patients with known or suspected coronary artery disease, computed tomography angiography can identify lesions associated with a significantly increased risk of acute coronary syndrome, according to a study published in the June 30 issue of the Journal of the American College of Cardiology.

Abstract
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High Hemoglobin Targets Not Helpful to Kidney Patients

TUESDAY, June 23 (HealthDay News) -- Aiming for a high hemoglobin target when treating chronic kidney disease patients for anemia is not more beneficial than targeting a lower level, according to a study published in the June 22 issue of the Archives of Internal Medicine, while a second study in the same issue found that chronic kidney disease patients are at increased risk of hyperkalemia.

Abstract - Clement
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Abstract - Einhorn
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Total Knee Arthroplasty Found Cost-Effective

TUESDAY, June 23 (HealthDay News) -- Among Medicare patients, total knee arthroplasty is cost-effective, especially when performed at high-volume hospitals, according to a study published in the June 22 issue of the Archives of Internal Medicine.

Abstract
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Invited Commentary (subscription or payment may be required)

Dog, Cat Bites Can Expose Victim to Many Pathogens

TUESDAY, June 23 (HealthDay News) -- Bites from pets are a common source of injury, and clinicians should be familiar with pathogens found in animal bites and the steps in managing these injuries, according to a review published in the July issue of The Lancet Infectious Diseases.

Abstract
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Sexual Activity Down Among Teens in Finland in Since 2000

TUESDAY, June 23 (HealthDay News) -- Sexual activity among adolescents and the abortion rate in Finland have dropped since 2000, according to a study in the July Obstetrics & Gynecology.

Abstract
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Combination Treatment Relieves Menstrual Migraines

TUESDAY, June 23 (HealthDay News) -- Sumatriptan and naproxen used in combination delivered both two-hour and sustained pain relief to women with dysmenorrhea who were suffering menstrual migraine headaches, according to a pair of studies reported in the July issue of Obstetrics & Gynecology.

Abstract
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Obesity Hikes Young Women's Risk of Endometrial Cancer

TUESDAY, June 23 (HealthDay News) -- Obese and overweight women younger than 55 have an elevated risk for endometrial cancer, especially if they stop menstruating at an early age, according to a study in the July issue of Obstetrics & Gynecology.

Abstract
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President Signs Tobacco Law, Acts on Medicare Coverage

MONDAY, June 22 (HealthDay News) -- President Barack Obama moved on two health care fronts today, signing new legislation to regulate tobacco industry marketing and announcing an agreement with the nation's pharmaceutical companies to reduce the cost of prescription drugs for Americans on Medicare who find themselves in the so-called "doughnut hole" coverage gap.

Family Smoking Prevention and Tobacco Control Act
Pharmaceutical Discounts for Seniors

Body Responds to Changes in Musical Rhythms

MONDAY, June 22 (HealthDay News) -- Regardless of individual musical preference, changes in musical tempo cause autonomic respiratory and cardiovascular responses, according to a study published on June 22 in Circulation.

Abstract
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Motor Function Declines Faster in Less Socially Active Elders

MONDAY, June 22 (HealthDay News) -- Older adults who do not participate frequently in social activities are likely to experience a more rapid decline in motor function than their more socially active counterparts, according to a study published in the June 22 issue of the Archives of Internal Medicine.

Abstract
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Failure to Pass on Test Results to Patients Common

MONDAY, June 22 (HealthDay News) -- It is common for patients undergoing outpatient tests to not be informed of clinically significant results, according to a study published in the June 22 issue of the Archives of Internal Medicine.

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Urinary Symptoms Linked to Metabolic Syndrome in Men

MONDAY, June 22 (HealthDay News) -- In men, there is a significant association between lower urinary tract symptoms and metabolic syndrome, according to a study published online June 18 in the Journal of Urology.

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Schizophrenia Linked to Increased Cancer Mortality

MONDAY, June 22 (HealthDay News) -- Among patients with schizophrenia, women have an increased risk of death from breast cancer and men have an increased risk of death from lung cancer, according to a study published online June 22 in Cancer.

Abstract
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Treatment May Protect Against Diet-Related Obesity

MONDAY, June 22 (HealthDay News) -- Angiotensin-converting enzyme (ACE) inhibition led to less gain of body weight and fat mass, as well as improved glucose tolerance in rats, according to research published online June 4 in Endocrinology.

Abstract
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Study Compares Combined and Single Cervical Tests

MONDAY, June 22 (HealthDay News) -- Liquid-based cytology (LBC) plus human papillomavirus (HPV) testing in women led to a small decrease in the detection rate of cervical intraepithelial neoplasia grade 3 or worse (CIN3+) in a second screening round, compared to only LBC; but when the rounds were combined, the use of both methods didn't detect more CIN3+ or CIN2+ than LBC alone, according to research published online June 18 in The Lancet Oncology.

Abstract
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Reinforced Infection Control Needed to Combat H1N1

MONDAY, June 22 (HealthDay News) -- Infection control messages aimed at health care workers should be reinforced in an effort to reduce the spread of novel influenza A (H1N1) virus, according to a study published in the June 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Racial Differences Evident in Alcohol-Related Suicides

MONDAY, June 22 (HealthDay News) -- There are significant racial and ethnic variations in the burden of alcohol-attributable suicides in the United States, according to a study published in the June 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Oxygen-Ozone Injections May Help Lower Back Pain

FRIDAY, June 19 (HealthDay News) -- Intramuscular paravertebral injections of oxygen and ozone may be helpful in relieving acute low back pain, according to research published in the June 1 issue of Spine.

Abstract
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Tea Polyphenols May Inhibit Prostate Cancer Progression

FRIDAY, June 19 (HealthDay News) -- Taking daily doses of green tea polyphenols in capsule form may someday have a role in the prevention and treatment of prostate cancer, according to a study published online June 19 in Cancer Prevention Research.

Abstract
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Ethnic Variation of Diabetes Prevalence Studied

FRIDAY, June 19 (HealthDay News) -- A number of racial and ethnic groups showed a higher diabetes prevalence compared with Caucasians, even among those who were not overweight or obese, according to research published in a 2009 Ethnicity & Disease.

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Continuous EEG Spots Hidden Brain Injury in Critical Care

FRIDAY, June 19 (HealthDay News) -- Continuous electroencephalography (EEG) may help to identify patients with otherwise undetectable seizures, according to a study published in the June issue of Critical Care Medicine, while a study published online April 13 in the Annals of Neurology found that intracortical EEG is better than scalp EEG for detection of secondary neuronal injury.

Abstract - Oddo
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Abstract - Waziri
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Co-Proxamol Withdrawal Results in Fewer Suicides

FRIDAY, June 19 (HealthDay News) -- There was a significant reduction in the number of accidental poisonings and suicides when the drug co-proxamol was withdrawn in 2005, and there has been no subsequent increase in the number of deaths involving other painkillers, according to a study published online on June 18 in BMJ.

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Many Stone Patients May Not See Urologist After ER

FRIDAY, June 19 (HealthDay News) -- Many patients visiting an emergency department with ureterolithiasis may not follow up with a urologist, according to research published in the June issue of Urology.

Abstract
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Incontinence Common in Women With Type 1 Diabetes

FRIDAY, June 19 (HealthDay News) -- Urinary tract infections (UTIs) and increased weight are associated with higher risk of urinary incontinence in women with type 1 diabetes, according to research published in the June issue of Urology.

Abstract
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Billing Claims Markers of Cardiovascular Events

FRIDAY, June 19 (HealthDay News) -- In older patients who undergo kidney transplantation, use of combined Medicare Parts A and B billing claims is a sensitive measure of cardiovascular events, according to a study published online June 18 in the Clinical Journal of the American Society of Nephrology.

Abstract
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Findings Uncover Genetic Links Involved In Neuroblastoma

THURSDAY, June 18 (HealthDay News) -- A common copy number variation at 1q21.1 plays a role in neuroblastoma susceptibility, and common variations in the BARD1 gene are associated with the aggressive form of the disease, according to two studies published in the June 18 Nature and the June Nature Genetics.

Abstract - Diskin
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Abstract - Capasso
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Treatment With MicroRNA Linked to Liver Cancer Benefit

THURSDAY, June 18 (HealthDay News) -- The systemic delivery of miR-26a, a microRNA, using adeno-associated virus was associated with protection from hepatocellular carcinoma progression in a mouse model of the disease, according to research published in the June 12 issue of Cell.

Abstract
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Drug Inhibits Restenosis in Diabetics After Stent

THURSDAY, June 18 (HealthDay News) -- The drug pioglitazone can help prevent restenosis after the placement of a bare-metal stent in a patient with type 2 diabetes mellitus, according to a study in the June Journal of the American College of Cardiology: Cardiovascular Interventions.

Abstract
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Contraceptives Spike Risk for Embolism in Black Women

THURSDAY, June 18 (HealthDay News) -- The risk for venous thromboembolism is higher among African American women who use hormonal contraceptives than those who don't, and may be further elevated for women with the sickle cell trait, according to a study reported in the June issue of the American Journal of Obstetrics & Gynecology.

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Drug Hikes Death Risk for Kidney Disease Patients

THURSDAY, June 18 (HealthDay News) -- Patients with kidney disease (diabetic nephropathy) receiving clopidogrel to inhibit blood clotting are at increased risk for death, according to a study reported in the May 15 American Journal of Cardiology.

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New Protein Panel Proposed for Ovarian Cancer Serum Test

THURSDAY, June 18 (HealthDay News) -- A panel of tests for multiple protein biomarkers of ovarian cancer, including CA-125, may be able to reliably detect the disease earlier than testing for CA-125 alone, according to a study reported in the June issue of the American Journal of Obstetrics & Gynecology.

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Ultrasound No Better Than History in Cerclage Decision

THURSDAY, June 18 (HealthDay News) -- Basing the decision to insert a cerclage in pregnant women at risk for preterm delivery on shortening of the cervix observed on ultrasound results in more suturing procedures, but no improvement in the incidence of preterm delivery, according to a study reported in the June issue of the American Journal of Obstetrics & Gynecology.

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Erythropoietin Improves Blood Flow in Ischemic Legs

THURSDAY, June 18 (HealthDay News) -- When delivered by gelatin microspheres, the angiogenic factor erythropoietin can safely improve blood flow in a mouse model of peripheral arterial disease, according to a study in the June 23 issue of the Journal of the American College of Cardiology.

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Macrophage Marker Linked to Survival in Melanoma

THURSDAY, June 18 (HealthDay News) -- Levels of a protein shed from anti-inflammatory macrophages and the level of macrophage infiltration into the tumor are associated with survival in patients with melanoma, according to a study published online June 15 in the Journal of Clinical Oncology.

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