Here are what the editors at HealthDay consider to be the most important developments in Urology for June 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Oncology Best Supportive Care Studies Faulted
TUESDAY, June 30 (HealthDay News) -- In oncology, best supportive care studies exhibit ethical and methodological shortcomings, and systematic bias or error that may be due to ad hoc supportive care and lack of standardized delivery, according to a study published online June 29 in the Journal of Clinical Oncology.
Human Fat Cells Used to Repair Mouse Bladder Tissue
THURSDAY, June 25 (HealthDay News) -- Japanese researchers have successfully cultured and differentiated human fat cells to produce smooth muscle cells to regenerate injured bladder tissue in mice, according to a report in the July issue of the Journal of Urology.
Olaparib May Benefit BRCA Mutation Carriers
WEDNESDAY, June 24 (HealthDay News) -- Olaparib, a new oral drug that inhibits poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP), may be an effective treatment for patients with cancer associated with the BRCA1 or BRCA2 mutation, according to a study published early online June 25 in the New England Journal of Medicine.
Urine Biomarkers Discovered for Acute Appendicitis
WEDNESDAY, June 24 (HealthDay News) -- The presence of certain protein biomarkers in the urine may be useful in the diagnosis of acute appendicitis, which can present with varied symptoms, according to a study reported online June 24 in the Annals of Emergency Medicine.
Dual Drug Therapy Found Effective in Prostate Cancer
WEDNESDAY, June 24 (HealthDay News) -- In a phase II clinical trial, treatment with docetaxel and capecitabine dramatically reduced prostate-specific antigen (PSA) levels in a cohort of patients with metastatic, castrate-resistant prostate cancer (CRPC), according to a report in the July issue of the Journal of Urology.
Americans Paying for More of Their Health Care Costs
WEDNESDAY, June 24 (HealthDay News) -- Out-of-pocket costs are rising for Americans with health care coverage, including premiums, deductibles and copayments, according to a new June 23 report from the U.S. Department of Health & Human Services.
High Hemoglobin Targets Not Helpful to Kidney Patients
TUESDAY, June 23 (HealthDay News) -- Aiming for a high hemoglobin target when treating chronic kidney disease patients for anemia is not more beneficial than targeting a lower level, according to a study published in the June 22 issue of the Archives of Internal Medicine, while a second study in the same issue found that chronic kidney disease patients are at increased risk of hyperkalemia.
President Signs Tobacco Law, Acts on Medicare Coverage
MONDAY, June 22 (HealthDay News) -- President Barack Obama moved on two health care fronts today, signing new legislation to regulate tobacco industry marketing and announcing an agreement with the nation's pharmaceutical companies to reduce the cost of prescription drugs for Americans on Medicare who find themselves in the so-called "doughnut hole" coverage gap.
Urinary Symptoms Linked to Metabolic Syndrome in Men
MONDAY, June 22 (HealthDay News) -- In men, there is a significant association between lower urinary tract symptoms and metabolic syndrome, according to a study published online June 18 in the Journal of Urology.
Reinforced Infection Control Needed to Combat H1N1
MONDAY, June 22 (HealthDay News) -- Infection control messages aimed at health care workers should be reinforced in an effort to reduce the spread of novel influenza A (H1N1) virus, according to a study published in the June 19 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Office Urologic Procedures Pose Little Risk
FRIDAY, June 19 (HealthDay News) -- Cystoscopy and transrectal ultrasound-guided prostate biopsy performed in the office setting appear to pose minimal risk to patients, according to research published in the June issue of Urology.
Digital Rectal Exam Remains Key in Men With Low PSA
FRIDAY, June 19 (HealthDay News) -- Due to the number of men who may have aggressive prostate cancers despite a low prostate specific antigen (PSA), digital rectal exams (DREs) remain important in detecting early cancer, according to research published in the June issue of the Journal of Urology.
Tea Polyphenols May Inhibit Prostate Cancer Progression
FRIDAY, June 19 (HealthDay News) -- Taking daily doses of green tea polyphenols in capsule form may someday have a role in the prevention and treatment of prostate cancer, according to a study published online June 19 in Cancer Prevention Research.
Many Stone Patients May Not See Urologist After ER
FRIDAY, June 19 (HealthDay News) -- Many patients visiting an emergency department with ureterolithiasis may not follow up with a urologist, according to research published in the June issue of Urology.
Incontinence Common in Women With Type 1 Diabetes
FRIDAY, June 19 (HealthDay News) -- Urinary tract infections (UTIs) and increased weight are associated with higher risk of urinary incontinence in women with type 1 diabetes, according to research published in the June issue of Urology.
Selenium Linked to Prostate Cancer Aggressiveness
THURSDAY, June 18 (HealthDay News) -- High selenium levels are associated with more aggressive disease in men with prostate cancer, but only in men with a particular gene variant, according to a study published online June 15 in the Journal of Clinical Oncology.
Glove Perforation Raises Odds of Surgical Site Infection
THURSDAY, June 18 (HealthDay News) -- Surgical glove perforation significantly increases the risk of surgical site infection in procedures where surgical antimicrobial prophylaxis is not applied, according to a study published in the June issue of the Archives of Surgery.
Individual Mandate for Health Insurance Affordable and Fair
WEDNESDAY, June 17 (HealthDay News) -- Reforming the health insurance market so that all individuals are required to obtain at least a minimum amount of health insurance would eliminate the problem of adverse selection that the current system enables insurers to avoid, according to a perspective published online June 17 in the New England Journal of Medicine.
Sweeping Medical Reforms Lack Medical Liability Element
MONDAY, June 15 (HealthDay News) -- Three approaches to medical reform currently under discussion in the United States all have pros and cons, and questions remain over whether or not the reform package should include changes to the medical liability system, according to an article published online June 15 in the New England Journal of Medicine.
Behavioral Intervention May Help Overactive Bladder
MONDAY, June 15 (HealthDay News) -- Tolterodine extended release, along with a behavioral intervention, may lead to treatment satisfaction in patients with overactive bladder who were previously dissatisfied with antimuscarinics, according to research published in the June issue of the Journal of Urology.
Bill Giving FDA Authority Over Tobacco on Way to President
FRIDAY, June 12 (HealthDay News) -- Legislation giving the U.S. Food and Drug Administration (FDA) regulatory control over tobacco products is headed to the White House for President Obama's signature, as health organizations continue to applaud the action.
Senate Approves Bill Giving FDA Authority Over Tobacco
THURSDAY, June 11 (HealthDay News) -- The U.S. Senate has passed a measure that would give the U.S. Food and Drug Administration (FDA) broad authority over the advertising, sale, and manufacture of tobacco products, an action that is being applauded by the American Medical Association, among others.
Dry Eye Affects 1.68 Million Older Men in U.S.
THURSDAY, June 11 (HealthDay News) -- Dry eye disease affects 1.68 million U.S. men age 50 and older, and those who have high blood pressure, an enlarged prostate, or use antidepressants are at elevated risk, according to a study reported in the June Archives of Ophthalmology.
Prostate Cancer Treatment Side Effects Explored
THURSDAY, June 11 (HealthDay News) -- The treatments for localized prostate cancer -- prostatectomy, brachytherapy, and external radiation -- have varied side effect profiles, and these should be taken into consideration in the selection of a treatment, according to a study published online June 9 in the Journal of the National Cancer Institute.
Androgen Suppression Length Important in Prostate Cancer
WEDNESDAY, June 10 (HealthDay News) -- In combination with radiation treatment, androgen suppression is effective in increasing survival in men with prostate cancer, but only when given for several years, according to a study in the June 11 issue of the New England Journal of Medicine.
Androgen Deprivation Linked to Diabetes in Prostate Cancer
WEDNESDAY, June 10 (HealthDay News) -- Researchers have found that androgen deprivation therapy (ADT) is associated with a higher risk of diabetes and fragility fractures in men with prostate cancer, according to a study published online June 8 in the Journal of Clinical Oncology. In a related study in the same issue, pretreatment prostate specific antigen (PSA) dynamics do not add predictive value for prostate cancer outcomes.
Signaling Network Identified in Prostatic Hyperplasia Model
FRIDAY, June 5 (HealthDay News) -- Analysis of a rat model of benign prostatic hyperplasia (BPH) has identified a cellular signaling network and targets that could be exploited for therapeutics, according to a study published online May 14 in Endocrinology.
Many U.K. Trained Doctors Stay in National Health Service
WEDNESDAY, June 3 (HealthDay News) -- The majority of domestic medical students in Britain work in the National Health Service (NHS) after graduation, as do the majority of doctors from overseas who go to the country for training, with men and women choosing similar career paths, according to a study published online June 3 in BMJ.
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