Create Account | Sign In: Author or Forum

 
News  |  Journals  |  Conferences  |  Opinion  |  Articles  |  Forums  |  Twitter    
 
Category: Dermatology | Family Medicine | Internal Medicine | Pathology | Surgery | Journal

Back to Journal Articles

Rough Microdermabrasion May Be Better for Skin Remodeling

Last Updated: October 23, 2009.

 

Study finds coarse-grit induces dermal remodeling not seen with medium-grit

Share |

Comments: (0)

Tell-a-Friend

 

  Related
 
Using a coarse-grit hand piece to conduct microdermabrasion prompts sun-damaged skin to remodel itself in a process similar to wound healing, and may be more effective in dermal remodeling than medium-grit use, according to a study in the October issue of the Archives of Dermatology.

FRIDAY, Oct. 23 (HealthDay News) -- Using a coarse-grit hand piece to conduct microdermabrasion prompts sun-damaged skin to remodel itself in a process similar to wound healing, and may be more effective in dermal remodeling than medium-grit use, according to a study in the October issue of the Archives of Dermatology.

Darius J. Karimipour, M.D., of the University of Michigan in Ann Arbor, and colleagues conducted a study of 40 adults aged 50 to 83 years who had clinically photodamaged forearms and who underwent focal microdermabrasion and provided skin biopsies after treatment with hand pieces of varied abrasiveness.

When the subjects underwent coarse-grain microdermabrasion, the skin responded by producing a wound-healing response of rapidly increased cytokeratin 16 production, and activation of the AP-1 transcription factor in the epidermis, the researchers discovered. Dermal remodeling also occurred with induction of types I and III procollagen and collagen production enhancers, the investigators report, while a medium-grit hand piece did not generate the same dermal remodeling results.

"Optimization of these molecular effects is likely the result of more aggressive treatment with a more abrasive hand piece," the authors write. "To the extent that molecular changes can predict clinical outcome, aggressive coarse-grit microdermabrasion should elicit significant skin rejuvenation. Further studies will determine whether microdermabrasion, if performed aggressively, has the capacity to become a worthwhile resurfacing procedure that results in noticeable cosmetic improvement while minimizing patient morbidity and downtime."

Abstract
Full Text (subscription or payment may be required)

Copyright © 2009 ScoutNews, LLC. All rights reserved.


Previous: American Academy of Pediatrics, Oct. 17-20, 2009 Next: Neonatal Outcomes Examined in Cancer Pregnancies

Reader comments on this article are listed below. Review our comments policy.


Submit your opinion:

Name:

Email:

Location:

URL:

Remember my personal information

Notify me of follow-up comments?

advertisement.gif (61x7 -- 0 bytes)
 

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

Doctors Lounge Membership Application

 
     

 advertisement.gif (61x7 -- 0 bytes)

 

 

Useful Sites
MediLexicon
  Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us
Copyright © 2001-2014
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Advertising
Links | Humor
Forum Archive
CME | Conferences

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.