Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for November 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Study Predicts Hep C Therapy Will Prevent Few Deaths
MONDAY, Nov. 30 (HealthDay News) -- If present trends continue in the United States, only 14.5 percent of future hepatitis C-related deaths will be prevented by antiviral treatment, which may be due to a lack of patients diagnosed and referred for treatment, according to a study in the December issue of Hepatology.
Cigarettes Teeming With Bacteria, Other Pathogens
MONDAY, Nov. 30 (HealthDay News) -- Cigarettes contain more than a dozen different types of bacteria, as well as other harmful pathogens that could play a role in smokers' increased risk of infectious and chronic respiratory diseases, according to a study published online Oct. 22 in Environmental Health Perspectives.
Needlestick Injuries Common Among Medical Students
MONDAY, Nov. 30 (HealthDay News) -- The underdeveloped skills of medical students puts them at risk of contracting hepatitis and HIV due to needlestick injuries which frequently go unreported, according to a study published in the December issue of Academic Medicine.
West Nile Virus Slipped Through Blood Screening Net
MONDAY, Nov. 30 (HealthDay News) -- West Nile virus still poses a threat to organ transplant and blood product recipients, despite the introduction of nationwide screening, according to a report published in the Nov. 20 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
General Population May Have Some Immunity to Swine Flu
THURSDAY, Nov. 26 (HealthDay News) -- Swine flu has many immunological similarities to seasonal flu, and the general population has some pre-existing immunity to swine flu, suggesting that swine flu infection may not be as severe as feared, according to a study published online Nov. 16 in the Proceedings of the National Academy of Sciences.
CDC: Worrisome Spike Seen in Pneumococcal Disease
WEDNESDAY, Nov. 25 (HealthDay News) -- H1N1 vaccine supply continues to increase, but serious pneumococcal infections are on the rise around the country, according to a Nov. 25 press briefing held by the U.S. Centers for Disease Control and Prevention.
Most Medical Journals Have Conflict of Interest Policies
TUESDAY, Nov. 24 (HealthDay News) -- Most high impact factor journals have publicly available conflict of interest statement policies, but there is a great deal of variation among journals, which could be confusing for authors, according to a study in the Nov. 25 issue of the Journal of the American Medical Association.
Home-Based Care Effective for Advanced HIV Infection
TUESDAY, Nov. 24 (HealthDay News) -- Home-based antiretroviral care is as effective as facility-based care for Ugandan patients with advanced HIV infection at much lower cost to the patient, according to a study published online Nov. 24 in The Lancet.
Vaccine Appears to Have No Impact on Pregnancy Outcome
TUESDAY, Nov. 24 (HealthDay News) -- There is no evidence that vaccination with the quadrivalent human papillomavirus (HPV) vaccine is harmful to the fetus, but vaccination during pregnancy is still not recommended, according to two studies published in the December issue of Obstetrics & Gynecology.
Sexually Transmitted Infection Found Common in Teen Girls
MONDAY, Nov. 23 (HealthDay News) -- In adolescent girls, the prevalence of sexually transmitted infections is substantial, and human papillomavirus (HPV) is the most common infection, according to a study published online Nov. 23 in Pediatrics.
Winter Flu May Push Pediatric Intensive Care to Limit
MONDAY, Nov. 23 (HealthDay News) -- Demand for pediatric intensive care unit beds in the United Kingdom is likely to exceed demand during the anticipated flu pandemic this winter, according to a study in the December issue of the Archives of Disease in Childhood.
High HLA Gene Expression May Slow AIDS Progression
MONDAY, Nov. 23 (HealthDay News) -- High HLA-C expression on cell surfaces in individuals infected with HIV appears to slow progression to full-blown AIDS, while better controlling plasma viral loads, according to a study published online Nov. 22 in Nature Genetics.
H1N1 Influenza Rates Fall in Some Parts of United States
MONDAY, Nov. 23 (HealthDay News) -- Although H1N1 influenza is still widespread in most states, there have been declines in some areas of the country, a federal health official announced Nov. 20 at a U.S. Centers for Disease Control and Prevention press briefing.
Video Found to Be Useful in Pelvic Inflammatory Disease
FRIDAY, Nov. 20 (HealthDay News) -- Adolescent girls who watch a community-specific video intervention at the time of diagnosis of pelvic inflammatory disease may be significantly more likely to have their sexual partners treated, according to a study published online Sept. 4 in the Journal of Pediatric and Adolescent Gynecology.
Pandemic Influenza May Hurt Economy in United Kingdom
FRIDAY, Nov. 20 (HealthDay News) -- Although pandemic influenza may only decrease the gross domestic product (GDP) by up to 4.3 percent in the United Kingdom, school closures and absenteeism from work due to government regulations or fear of infection may negatively impact the economy and potentially increase the effect of the recession, according to a study published Nov. 19 in BMJ.
Cervical Cancer Screening Guidelines Updated
FRIDAY, Nov. 20 (HealthDay News) -- Women should not start getting routine cervical cancer tests until age 21, and then they should repeat them every two years instead of annually though age 30, according to new guidelines from the American College of Obstetricians and Gynecologists (ACOG) published in Obstetrics & Gynecology.
Herpes Virus Shedding Studied With Mathematical Model
THURSDAY, Nov. 19 (HealthDay News) -- People infected with herpes simplex virus 2 (HSV-2) experience almost constant releases of small numbers of viruses from the neurons that host them into the genital tract, which may make prevention of person-to-person transmission difficult, according to a mathematical model of HSV-2 behavior described in a paper published online Nov. 18 in Science Translational Medicine.
Trivalent Vaccine Has Minimal Effect on H1N1
TUESDAY, Nov. 17 (HealthDay News) -- Seasonal influenza vaccination neither decreases nor increases the risk for acquiring pandemic H1N1 illness, according to research published in the Nov. 13 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
People at High Risk of Swine Flu Warned to Avoid Hajj
MONDAY, Nov. 16 (HealthDay News) -- Public health consultants to the Saudi Arabian government have recommended that pilgrims in categories at high risk for H1N1 swine who are planning to take part in the 2009 Hajj should postpone their participation until another year, according to a paper published online Nov. 14 in The Lancet.
Depression Linked to Immune Response in Pregnancy
FRIDAY, Nov. 13 (HealthDay News) -- Women with greater symptoms of depression may experience increased inflammatory responses to influenza vaccination and potentially infectious illness during pregnancy, according to research published in Brain, Behavior, and Immunity.
Another Swine Flu Vaccine Approved for Children
FRIDAY, Nov. 13 (HealthDay News) -- CSL Limited's H1N1 influenza vaccine has been approved by the U.S. Food and Drug Administration to include children 6 months and older, the agency said. Previously, the shot had been approved only for adults.
Campaign to Decrease Illegal Antibiotic Use Assessed
FRIDAY, Nov. 13 (HealthDay News) -- An educational initiative may not be sufficient to decrease use of antibiotics without a prescription (WORx) by the Latino community, according to a study in the November/December issue of the Annals of Family Medicine.
CDC: New H1N1 Tracking Method Ups Estimates
THURSDAY, Nov. 12 (HealthDay News) -- At least 22 million Americans have been infected with H1N1 since April, and approximately 3,900 people have died, including an estimated 540 children, according to information presented at the U.S. Centers for Disease Control and Prevention's Nov. 12 H1N1 press conference.
Common Infections May Increase Risk of First Stroke
THURSDAY, Nov. 12 (HealthDay News) -- Exposure to five common infections potentially linked to atherosclerosis may increase the risk for first stroke, according to the Northern Manhattan Study published online Nov. 9 in the Archives of Neurology.
Risk Communication Key to Keeping H1N1 Deaths Down
THURSDAY, Nov. 12 (HealthDay News) -- Hospital preparedness and risk communication are crucial to the reduction in mortality due to H1N1 influenza, according to a study published online Nov. 12 in The Lancet.
Study Finds Costs of Quality Programs Burden Practices
WEDNESDAY, Nov. 11 (HealthDay News) -- The cost of providing data and support for health system quality-improvement programs can put a significant burden on primary care practices, and changes in the outcomes of trials are often made without being disclosed, according to two studies in the November/December Annals of Family Medicine.
Medical Errors Disclosure Can Help Physicians and Patients
WEDNESDAY, Nov. 11 (HealthDay News) -- Physicians are willing to share their experiences of making diagnostic errors, and analyzing them systematically helps point the way to improve future diagnoses, according to a study in the Nov. 9 issue of the Archives of Internal Medicine, while a second study in the same issue found that patients give higher quality ratings when adverse events are disclosed.
Uptake of Adult Vaccination Varies Widely in Urban Areas
TUESDAY, Nov. 10 (HealthDay News) -- There are wide variations in the uptake of pneumococcal polysaccharide vaccine (PPV) and influenza vaccine in adults in urban areas, and physicians' practice characteristics influence the likelihood of their patients getting vaccinated, according to a study in the November/December Annals of Family Medicine.
Pollutants May Increase Bronchiolitis Risk in Infants
MONDAY, Nov. 9 (HealthDay News) -- Certain types of traffic-related air pollutants may raise the risk of bronchiolitis in infants, according to research published in the Nov. 15 issue of the American Journal of Respiratory and Critical Care Medicine.
Novel Vaccine Tested for Vulvar Neoplasia
WEDNESDAY, Nov. 4 (HealthDay News) -- Researchers from the Netherlands have developed a vaccine for vulvar intraepithelial neoplasia linked to the human papillomavirus-16 (HPV-16) that within a year produced a complete clinical response in 47 percent of women receiving it, according to a study in the Nov. 5 issue of the New England Journal of Medicine.
Stats Helps Paint Picture of H1N1 Hospitalizations
TUESDAY, Nov. 3 (HealthDay News) -- The age of people hospitalized with H1N1 influenza infection in California during the summer of 2009 was typically younger than the age commonly seen with seasonal influenza, and infants had the highest rates of hospitalization and those aged 50 and older had the highest mortality, according to research published in the Nov. 4 issue of the Journal of the American Medical Association.
Pregnant Women Need Only One Dose of H1N1 Vaccine
TUESDAY, Nov. 3 (HealthDay News) -- One dose of H1N1 vaccine is sufficient for pregnant women, though young children need two doses, according to a Nov. 2 announcement from the U.S. National Institute of Allergy and Infectious Diseases (NIAID).
Perioperative Beta-Blocker Therapy Guidelines Updated
MONDAY, Nov. 2 (HealthDay News) -- The American College of Cardiology Foundation/American Heart Association (ACCF/AHA) recommends perioperative beta-blocker use dependent on careful consideration of the benefits and risks to an individual patient, according to an update of the 2007 guidelines outlining cardiovascular evaluation and care for non-cardiac surgery published online Nov. 2 in the Journal of the American College of Cardiology.
Background Disease Rates Important in H1N1 Pandemic
MONDAY, Nov. 2 (HealthDay News) -- During mass immunization with pandemic H1N1 influenza vaccines, awareness of background rates of disease is essential for assessing vaccine safety, and may help allay vaccine-associated fears among the general public, according to an article published online Oct. 31 in The Lancet.
Pediatric H1N1 Influenza Deaths Reach at Least 114
MONDAY, Nov. 2 (HealthDay News) -- As of Friday, 19 children had died of H1N1 influenza in the past week, bringing the total number of pediatric deaths from the disease to at least 114, the U.S. Centers for Disease Control and Prevention announced at an Oct. 30 news conference.
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