Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for December 2009. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Precautions and Training Can Reduce Scalpel Injuries
THURSDAY, Dec. 31 (HealthDay News) -- Although less common than needle-stick injuries, cuts from scalpels also put operating room personnel at risk and can be reduced by closely following safety precautions and taking advantage of new technology, according to a study in the December issue of the AORN Journal.
Omeprazole, Surgery Found Effective for Reflux Disease
WEDNESDAY, Dec. 30 (HealthDay News) -- In patients with chronic gastroesophageal reflux disease, more patients stayed in clinical remission after anti-reflux surgery than with long-term omeprazole, though surgery was associated with postoperative complaints, according to research published in the December issue of Clinical Gastroenterology and Hepatology.
PPIs Linked to Lower Cancer Risk in Barrett's Esophagus
MONDAY, Dec. 28 (HealthDay News) -- Patients with Barrett's esophagus who take proton pump inhibitors (PPIs) have a lower risk of high-grade dysplasia and esophageal cancer, according to research published in the December issue of Clinical Gastroenterology and Hepatology.
Study Evaluates New Assays for Diagnosing Liver Diseases
MONDAY, Dec. 28 (HealthDay News) -- New assays may aid in the diagnosis of chronic autoimmune liver disorders, according to research published in the December issue of Clinical Gastroenterology and Hepatology.
Higher Surgery Risks in Elderly Demand Special Attention
FRIDAY, Dec. 25 (HealthDay News) -- Common and emergency surgery carries elevated risks of mortality and complications in the elderly, and clinicians should counsel patients on these risks and make every effort to mitigate them, according to a pair of studies in the December issue of the Archives of Surgery.
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Abstract - McGillicuddy
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Some Pre-Op Weight Loss Cuts Gastric Bypass Complications
THURSDAY, Dec. 24 (HealthDay News) -- Increased weight loss before gastric bypass surgery is associated with fewer complications after surgery, according to a study reported in the December issue of the Archives of Surgery.
Study Finds Stent, Laparoscopy Superior to Open Surgery
THURSDAY, Dec. 24 (HealthDay News) -- Instead of performing emergency open surgery on a colon cancer patient with an obstructing tumor, placement of a metal stent can open a bowel pathway until the tumor is removed via less invasive laparoscopy, according to a study in the December issue of the Archives of Surgery.
Over 85s Function Well Despite Disease and Disability
WEDNESDAY, Dec. 23 (HealthDay News) -- Elders over the age of 85 report good health and functional ability despite the fact that they have to contend with a range of diseases and disabilities; however, as the fastest growing segment of the world's population, the health needs of future generations of over 85s represent a profound challenge, according to a study published online Dec. 22 in BMJ.
TAK1 Protein Found Essential for Proper Liver Function
TUESDAY, Dec. 22 (HealthDay News) -- Deletion of a cellular signaling protein specifically in hepatocytes leads to hepatocyte death and compensatory liver damage and cancer, according to a study published online Dec. 18 in the Proceedings of the National Academy of Sciences.
More Computed Tomography May Mean More Cancer Risk
WEDNESDAY, Dec. 16 (HealthDay News) -- The growing use of computed tomography (CT) scans will cause thousands more cases of cancer in the future, according to a study published in the Dec. 14/28 issue of the Archives of Internal Medicine, while a second study in the same issue found that the dose and cancer risk of CT scans varies widely from case to case.
Rome II Criteria Beneficial for Gastrointestinal Disorders
TUESDAY, Dec. 15 (HealthDay News) -- Family pediatricians can properly diagnose and manage functional gastrointestinal disorders (FGIDs) using the so-called Rome II criteria, according to research published online Dec. 14 in Pediatrics.
Milk Thistle Could Be Useful During Leukemia Treatment
MONDAY, Dec. 14 (HealthDay News) -- The use of the herb milk thistle may reduce liver toxicity in children with acute lymphoblastic leukemia undergoing chemotherapy, according to research published online Dec. 14 in Cancer.
SSRIs Linked to Upper Gastrointestinal Bleeding
MONDAY, Dec. 14 (HealthDay News) -- Selective serotonin reuptake inhibitors (SSRIs) are associated with an increased risk of upper gastrointestinal bleeding, which warrants caution when prescribing these drugs in patients at elevated risk for this type of bleeding, according to research published in the December issue of Clinical Gastroenterology and Hepatology.
Protocol Leads to Ileitis Diagnosis in Most Likely Cases
FRIDAY, Dec. 11 (HealthDay News) -- A standard protocol for investigating suspected acute ileitis can lead to a definitive diagnosis in the majority of cases, according to research published in the November issue of Clinical Gastroenterology and Hepatology.
Myelosuppression Risk During Thiopurine Therapy Is Concern
FRIDAY, Dec. 11 (HealthDay News) -- The risk of severe myelosuppression in patients with inflammatory bowel disease using thiopurine therapy warrants monitoring the patients during their first two months of therapy, according to research published in the November issue of Clinical Gastroenterology and Hepatology.
Patients Often Lack Knowledge of Their Own Medications
THURSDAY, Dec. 10 (HealthDay News) -- Patients routinely under-report, or even over-report, their outpatient and inpatient medications, and should be included in hospital medication management to improve safety, according to a study published online Dec. 10 in the Journal of Hospital Medicine.
Liver Transplant Patient and Graft Survival Studied
MONDAY, Dec. 7 (HealthDay News) -- Patient survival and graft survival after liver transplantation are similar for patients whose transplant results from either nonalcoholic steatohepatitis (NASH) or alcoholic cirrhosis (ETOH), according to a study in the December issue of Liver Transplantation.
Smoking, Drinking Linked to Multiple Cancer Effects
MONDAY, Dec. 7 (HealthDay News) -- Long-term cigarette smoking is linked to a higher risk of colorectal cancer, and alcohol consumption before or after diagnosis of head or neck cancer reduces the chance of survival, according to two studies in the December Cancer Epidemiology, Biomarkers & Prevention.
Guidance for Platelet Therapy Before Surgery Provided
FRIDAY, Dec. 4 (HealthDay News) -- In patients with coronary artery disease who need an elective endoscopic gastrointestinal procedure with a high risk of bleeding, cessation of antiplatelet treatment should be avoided for at least six months after undergoing revascularization and stent placement, according to a review in the Dec. 8 issue of the Journal of the American College of Cardiology.
Metabolic Syndrome Prevalent After Liver Transplant
THURSDAY, Dec. 3 (HealthDay News) -- Patients who receive liver transplants are at high risk for developing metabolic syndrome and resulting cardiovascular complications, but the impact on mortality and long-term survival are inconclusive, according to a review in the December Liver Transplantation.
Lipid Profile of Nonalcoholic Fatty Liver Disease Determined
WEDNESDAY, Dec. 2 (HealthDay News) -- Patients with nonalcoholic fatty liver disease (NAFL) have increased lipid production and changes in enzymes involved in the metabolism of lipids and fatty acids, according to a study in the December issue of Hepatology.
Cetuximab Linked to Resection of Liver Metastases
WEDNESDAY, Dec. 2 (HealthDay News) -- In patients with colorectal liver metastases, chemotherapy with cetuximab was associated with high rates of tumor response and resection of metastases, according to research published online Nov. 25 in The Lancet Oncology.
Zegerid OTC Approved for Frequent Heartburn
WEDNESDAY, Dec. 2 (HealthDay News) -- Merck & Co.'s Zegerid OTC (omeprazole/sodium bicarbonate) has been approved by the U.S. Food and Drug Administration to treat frequent heartburn, the company said Wednesday in a news release.
Morphologic Changes Gauge Liver Cancer Therapy Response
TUESDAY, Dec. 1 (HealthDay News) -- A method to assess the effect of chemotherapy on liver tumors based on morphologic changes observed on computed tomography (CT) was found to be significantly associated with pathologic response as well as with patient survival, according to a study in the Dec. 2 Journal of the American Medical Association.
Women Researchers Lag Behind Men in Grant Awards
TUESDAY, Dec. 1 (HealthDay News) -- Female physicians with a proven interest in research are less likely to receive prestigious research grants from the National Institutes of Health (NIH) than are male physicians, according to a study in the Dec. 1 issue of the Annals of Internal Medicine.
Mortality Lower With Aspirin After Therapy for Ulcer
TUESDAY, Dec. 1 (HealthDay News) -- Patients who have experienced peptic ulcer bleeding on low-dose aspirin and who undergo endoscopic hemostatic therapy for their ulcers have increased risk for recurrent bleeding if they resume taking aspirin, but have lowered risk of death, according to a study published online Nov. 30 in the Annals of Internal Medicine.
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