Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for January 2010. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
No-Sedation Protocol Shown to Reduce Ventilation Time
FRIDAY, Jan. 29 (HealthDay News) -- In critically ill patients receiving mechanical ventilation, a protocol of no sedation may reduce the number of days that ventilation is required, according to a study published online Jan. 29 in The Lancet.
Increased Medicare Copayments Affect Care Usage
WEDNESDAY, Jan. 27 (HealthDay News) -- In elderly patients, increasing copayments for ambulatory care may result in adverse health consequences and increased health care spending, according to a study in the Jan. 28 issue of the New England Journal of Medicine.
Insulin Treatments for Septic Shock Compared
TUESDAY, Jan. 26 (HealthDay News) -- Among septic shock patients treated with hydrocortisone, intensive insulin therapy did not improve mortality compared to conventional insulin therapy, with or without the further addition of fludrocortisone, according to a study in the Jan. 27 Journal of the American Medical Association.
Serum Procalcitonin Levels May Help Guide Antibiotic Use
MONDAY, Jan. 25 (HealthDay News) -- In patients with suspected severe bacterial infection, employing antibiotics judiciously based on the serum levels of the calcitonin precursor hormone procalcitonin can reduce antibiotic exposure without increased mortality, according to a study published online Jan. 23 in The Lancet.
Car Crash Trauma Often Under-Detected in Elderly
MONDAY, Jan. 25 (HealthDay News) -- Elderly people involved in motor vehicle crashes (MVCs) are often under-triaged and inappropriately treated for injuries that go undetected, according to a study in the January issue of the Journal of Emergency Nursing.
New Protocol Cuts Radiation Dose to Embolism Patients
MONDAY, Jan. 25 (HealthDay News) -- Implementing a new protocol for the judicious use of ventilation-perfusion (V/Q) scanning and computed tomography pulmonary angiography (CTPA) in patients with suspected pulmonary embolism reduced patient radiation exposure by 20 percent without increasing the false-negative rate, according to a study in the February issue of the American Journal of Roentgenology.
Quitting Smoking Can Increase Lung Cancer Survival Odds
FRIDAY, Jan. 22 (HealthDay News) -- Early-stage lung cancer patients who are smokers when they are diagnosed may significantly increase their chances of survival if they quit smoking, according to a study published online Jan. 21 in BMJ.
Study Finds Red Yeast Rice Efficacy Comparable to Statin
THURSDAY, Jan. 21 (HealthDay News) -- The alternative therapy red yeast rice performs comparably to the lipid-lowering drug pravastatin in reducing low-density lipoprotein (LDL) cholesterol levels in patients who had previously had to discontinue statin therapy because of muscle pain, according to a study in the Jan. 15 issue of the American Journal of Cardiology.
Higher Rate Than Estimated of H1N1 in U.K. Children
THURSDAY, Jan. 21 (HealthDay News) -- In the 2009 H1N1 influenza pandemic, children were much more vulnerable to infection than older people and, therefore, should be the primary target group for vaccination, according to a study published online Jan. 21 in The Lancet.
Emphysema Associated With Left Ventricular Issues
WEDNESDAY, Jan. 20 (HealthDay News) -- A greater extent of emphysema and more airflow obstruction is linked with poorer left ventricular filling and reduced cardiac output, according to research published in the Jan. 21 issue of the New England Journal of Medicine.
Reducing Dietary Salt Could Substantially Impact Health
WEDNESDAY, Jan. 20 (HealthDay News) -- Even modest reductions in Americans' dietary salt could substantially reduce cardiovascular events, including death, myocardial infarction and stroke, and should be a public health goal, according to a study published online Jan. 20 in the New England Journal of Medicine.
Tylenol Recall in Effect Includes Several Other Drugs
WEDNESDAY, Jan. 20 (HealthDay News) -- McNeil Consumer Healthcare has recently expanded its voluntary recall of some over-the-counter drugs to include about 500 lots of products, according to officials from the Office of Compliance in the Center for Drug Evaluation and Research at the U.S. Food and Drug Administration.
Diabetes Patients May Be at Higher Risk for Lung Diseases
WEDNESDAY, Jan. 20 (HealthDay News) -- The declining lung function of patients with diabetes puts them at increased risk of a range of lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, pneumonia and asthma, but not lung cancer, according to a study in the January issue of Diabetes Care.
Omega-3 Fatty Acids Linked to Less Change in Telomeres
TUESDAY, Jan. 19 (HealthDay News) -- Higher blood levels of omega-3 fatty acids are associated with a slower rate of telomere shortening in individuals with coronary artery disease, according to research published in the Jan. 20 issue of the Journal of the American Medical Association.
Sleep Apnea Severity Linked to Glucose Control in Diabetes
TUESDAY, Jan. 19 (HealthDay News) -- In type 2 diabetes patients with obstructive sleep apnea (OSA), the severity of the condition is positively correlated with poorer glucose control, according to a study published online Dec. 17 in the American Journal of Respiratory and Critical Care Medicine.
Smoke Linked to Sleep Issues for Children With Asthma
MONDAY, Jan. 18 (HealthDay News) -- Children with asthma who are exposed to secondhand smoke (SHS) have more sleep problems, according to research published online Jan. 18 in Pediatrics.
Number of People Infected by H1N1 Reaches 55 Million
MONDAY, Jan. 18 (HealthDay News) -- On Jan. 15, federal officials reported that, from mid-April through mid-December, an estimated 55 million people in the United States were infected with H1N1 influenza, including approximately 11,200 who died.
Disparities Seen in United Kingdom Cancer Care
FRIDAY, Jan. 15 (HealthDay News) -- In the United Kingdom, social factors such as age, gender, and socioeconomic status continue to affect access to hospital care for common cancers, according to a study published online Jan. 14 in BMJ.
Ticagrelor and Clopidogrel Compared in Heart Patients
THURSDAY, Jan. 14 (HealthDay News) -- Patients awaiting an invasive procedure for acute coronary syndrome have fewer instances of a combined end point of myocardial infarction (MI), stroke or cardiovascular death after treatment with the anti-clotting drug ticagrelor compared to standard care with clopidogrel, according to a study published online Jan. 14 in The Lancet.
Rituximab May Adversely Affect Immune Function
THURSDAY, Jan. 14 (HealthDay News) -- In patients with rheumatoid arthritis, treatment with rituximab may adversely affect the response to vaccines, according to two studies in the January issue of Arthritis & Rheumatism.
Biomedical Research Funding Shows Decline in 2008
TUESDAY, Jan. 12 (HealthDay News) -- After increasing since 1994, annual funding for biomedical research topped out at $90.2 billion in 2007 and began to decline in 2008, according to a study in the Jan. 13 issue of the Journal of the American Medical Association.
Greater Time in Front of TV Linked to Higher Mortality Risk
TUESDAY, Jan. 12 (HealthDay News) -- More time spent watching television is associated with a higher risk of cardiovascular and all-cause mortality, according to research published online Jan. 11 in Circulation.
Predictors of Middle-Age Lung Function Evaluated
FRIDAY, Jan. 8 (HealthDay News) -- Lung function in middle age is impacted by lifestyle factors, such as smoking, but also early childhood factors, such as low birth weight and respiratory infection, according to a study in the January issue of Chest.
Ipratropium Bromide for COPD May Up Cardiovascular Risks
FRIDAY, Jan. 8 (HealthDay News) -- The use of the short-acting anticholinergic ipratropium bromide for chronic obstructive pulmonary disease (COPD) within the past six months increases the risk of a cardiovascular event (CVE), while the long-acting anticholinergic bronchodilator tiotropium reduces mortality and cardiovascular events among patients with COPD, according to two studies in the January Chest.
Gap in Childhood Vaccination Coverage Is Narrowing
WEDNESDAY, Jan. 6 (HealthDay News) -- Vaccination coverage of American children is improving, with the gap between various sociodemographic groups narrowing, according to a study published online Jan. 5 in the American Journal of Preventive Medicine.
Radiofrequency Ablation Found Therapeutic for Lung Cancer
MONDAY, Jan. 4 (HealthDay News) -- Radiofrequency (RF) ablation appears to be a viable option for patients with primary non-small cell lung cancer (NSCLC) who aren't candidates for surgical treatment, according to research published in the January issue of Radiology.
Scans Identify Common Injuries After Earthquake
FRIDAY, Jan. 1 (HealthDay News) -- Multiple fractures and lung injuries were common in victims of a major earthquake in China who suffered crush thoracic trauma, according to research published in the January issue of Radiology.
Seniors Getting Chemo May Have More Adverse Events
FRIDAY, Jan. 1 (HealthDay News) -- Older patients with non-small-cell lung cancer (NSCLC) who get chemotherapy have higher risk of adverse events, necessitating a balance between symptom management and treatment risks, according to a study published online Dec. 28 in the Journal of Clinical Oncology.
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