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Back to Infections Drug Index
Brand Name: Biocef
Name: Cephalexin
Pregnancy Category B
Drug classes
Antibiotics
Cephalosporin (first generation)
Mechanism of action of Biocef
Bactericidal: inhibits synthesis of bacterial cell wall, causing
cell death.
Indications of Biocef
- Respiratory tract infections caused by S. pneumoniae, group A ?hemolytic
streptococci
- Dermatologic infections caused by staphylococci, streptococci
- Otitis media caused by S. pneumoniae, H. influenzae,
streptococci, staphylococci, M. catarrhalis
- Bone infections caused by staphylococci, P. mirabilis
- GU infections caused by E. coli, P. mirabilis, Klebsiella
Contraindications of Biocef
- Allergy to cephalosporins or penicillins
- Renal failure
- Lactation

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Adverse effectsof Biocef
- CNS: Headache, dizziness,
lethargy, paresthesias
- GI: Nausea, vomiting,
diarrhea, anorexia, abdominal pain, flatulence, pseudomembranous
colitis, liver toxicity
- Hematologic: Bone marrow
depression
- GU: Nephrotoxicity
- Hypersensitivity: Ranging
from rash, fever to anaphylaxis; serum sickness reaction
- Other: Superinfections
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