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Back to Infections Drug Index

Back to Penicillins


Amoxil, Polymox, Trimox,

Pregnancy Category B

Drug classes


Mechanism of action
Bactericidal: inhibits synthesis of cell wall of sensitive organisms, causing cell death.


  1. Infections due to susceptible strains of Haemophilus influenzae, E. coli, Proteus mirabilis, Neisseria gonorrhoeae, Streptococcus pneumoniae, streptococci, nonpencillinase-producing staphylococci 

Unlabeld use: Chlamydia trachomatis in pregnancy


  1. Contraindicated in the presence of allergies to penicillins,
    cephalosporins, or other allergens.

Use caution in the presence of renal disorders, lactation.

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Adverse effects 

  • CNS: Lethargy, hallucinations, seizures
  • GI: Glossitis, stomatitis, gastritis, sore mouth, furry tongue, black "hairy" tongue, nausea, vomiting, diarrhea, abdominal pain, bloody diarrhea, enterocolitis, pseudomembranous colitis, nonspecific hepatitis
  • Hematologic: Anemia, thrombocytopenia, leukopenia, neutropenia, prolonged bleeding time
    GU: Nephritis
  • Hypersensitivity reactions: Rash, fever, wheezing, anaphylaxis
  • Other: Superinfections-oral and rectal moniliasis, vaginitis

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