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Back to Infections Drug Index
Amoxicillin
Amoxil, Polymox, Trimox,
Wymox
Pregnancy Category B
Drug classes
Antibiotics
Penicillins
Mechanism of action
Bactericidal: inhibits synthesis of cell wall of sensitive organisms,
causing cell death.
Indications
- Infections due to susceptible strains of Haemophilus influenzae,
E. coli, Proteus mirabilis, Neisseria gonorrhoeae, Streptococcus
pneumoniae, streptococci, nonpencillinase-producing staphylococci
Unlabeld use: Chlamydia trachomatis in pregnancy
Contraindications
- Contraindicated in the presence of allergies to penicillins,
cephalosporins, or other allergens.
Use caution in the presence of renal disorders, lactation.
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Adverse effects
- CNS: Lethargy,
hallucinations, seizures
- GI: Glossitis, stomatitis,
gastritis, sore mouth, furry tongue, black "hairy" tongue, nausea,
vomiting,
diarrhea, abdominal pain, bloody diarrhea, enterocolitis,
pseudomembranous colitis, nonspecific hepatitis
- Hematologic: Anemia,
thrombocytopenia, leukopenia, neutropenia, prolonged bleeding time
GU: Nephritis
- Hypersensitivity
reactions: Rash, fever, wheezing,
anaphylaxis
- Other: Superinfections-oral
and rectal moniliasis, vaginitis
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