Back to Infections Drug Index
Name: Amantadine HCl
Pregnancy Category C
- Antiviral drug
- Antiparkinsonism drug
May inhibit penetration of influenza A virus into the host cell; may
increase dopamine release in the nigostriatal pathway of parkinsonism patients,
relieving their symptoms.
Prevention and treatment of influenza A virus respiratory infection,
especially in high-risk patients
Adjunct to late vaccination against influenza A virus, to provide interim
coverage; supplement to vaccination in immunodeficient patients; prophylaxis
when vaccination is contraindicated
Parkinson's disease and drug-induced extrapyramidal reactions
Allergy to drug product, seizures, liverdisease, eczematoid rash, psychoses,
CHF, renal disease, lactation.
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- CNS: Lightheadedness, dizziness, insomnia, confusion, irritability,
ataxia, psychosis, depression, hallucinations
- GI: Nausea, anorexia, constipation, dry mouth
- CV: CHF, orthostatic hypotension, dyspnea
- GU: Urinary retention