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Pregnancy Category C
Inhibits replication of some retroviruses, including HIV, HTLV III, LAV,
Treatment of adults with advanced HIV infection who are intolerant to
approved therapies with proven clinical benefit or who have experienced
significant clinical or immunologic deterioration while receiving these
therapies or for whom these therapies are contraindicated
Contraindicated in the presence of life-threatening allergy to any component,
Use caution in the presence of compromised bone marrow, impaired renal
or hepatic function.
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- CNS: Headache, insomnia, myalgia, asthenia, malaise, dizziness, paresthesia,
- GI: Nausea, GI pain, diarrhea, anorexia, vomiting, dyspepsia
- Hematologic: Agranulocytopenia, severe anemia requiring transfusions
- Other: Fever, diaphoresis, dyspnea, rash, taste perversion