Powered by


                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Ask a Doctor

   News via RSS







   Forum Archives





















   Primary Care






   Other Sections


   Research Tools

   Medical Tutorials

   Medical Software




Back to Infections Drug Index

Back to Antivirals

Name: Zidovudine

Pregnancy Category C

Drug classes

  • Antiviral drug

Therapeutic actions

Thymidine analogue isolated from the sperm of herring; drug is activated to a triphosphate form that inhibits replication of some retroviruses, including HIV, HTLV III, LAV, ARV.


Management of certain adult patients with symptomatic HIV infection (AIDS and advanced ARC) who have a history of cytologically confirmed P. carinii pneumonia or an absolute CD4 (T4 helper/inducer) lymphocyte count of less than 200/mm3 in the peripheral blood before therapy is begun (parenteral)

Management of patients with HIV infection who have evidence of impaired immunity

HIV-infected children older than 3 mo who have HIV-related symptoms or who are asymptomatic with abnormal laboratory values indicating significant HIV-related immunosuppression


Contraindicated in the presence of life-threatening allergy to any component, pregnancy, lactation.

Use caution in the presence of compromised bone marrow, impaired renal or hepatic function.

advertisement.gif (61x7 -- 0 bytes)

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application

Adverse effects

  • CNS: Headache, insomnia, myalgia, asthenia, malaise, dizziness, paresthesia, somnolence
  • GI: Nausea, GI pain, diarrhea, anorexia, vomiting, dyspepsia
  • Hematologic: Agranulocytopenia, severe anemia requiring transfusions
  • Other: Fever, diaphoresis, dyspnea, rash, taste perversion

 advertisement.gif (61x7 -- 0 bytes)



We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright 2001-2012 DoctorsLounge. All rights reserved.