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Forum Name: AIDS

Question: HIV inutero & babies


 adoptingmom - Fri Aug 29, 2008 5:27 pm

We are considering the adoption of a baby whose birthmom tested HIV + in 2007. We are told she is getting prenatal care & antiretroviral treatment. What are the chances of the baby being passed on HIV? They are planning a c-section too. How soon after the baby is born would they be able to test? How many tests would they do? How old would the baby be before we could be sure it is HIV free? Are there false positives and false negatives? What kind of treatment would the baby need in the meantime? Any info you can give me on this topic would be great. I am from a rural area where we just don't deal with this stuff so the drs. here are not real informed on the topic.
 Dr.M.jagesh kamath - Sun Nov 15, 2009 11:35 am

User avatar Hello,Mother to child transmission can be reduced from 25% to 2% by ARV ie anti retroviral therapy and avoiding breast feeding.DROM ie duration of ruptured membranes a significant cause of intrapartum transmission ie during delivery, is avoided by caserean section,while not affecting the in utero infection.Whether the child would develop the disease would depend on the virus load,treatment given,and maternal drug use.A DNA PCR test is conducted on the foetus at birth,2 weeks,4 to 6weeks,6 to 12 weeks,and 4 to 6 months.Pretest counselling,consent,post test counselling,and partner notifications are the procedures.By the age of 28 days the DNA PCR would give 96% sensitivity results.Non sub type B virus can give false negative results.A positive antibody test with western blot would confirm by 18 months.HIV can be presumptively excluded in nonbreastfed infants with two or more negative virologic tests,
with one test obtained at ≥14 days of age and one obtained at ≥1 month of age; or one negative virologic test result
obtained at ≥2 months of age; or one negative HIV antibody test result obtained at ≥6 months of age.This is only a basic guideline and more details could be got from your health provider.
 Dr.M.jagesh kamath - Sun Nov 15, 2009 11:59 am

User avatar Hello,Zidovudine prophylaxis is given to all infants exposed to HIV inutero reduces relatively the risk of vertical transmission.This is given atleast for 6 weeks.Best wishes.

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