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Forum Name: Miscellaneous Nephrology Topics

Question: Estimated GFR


 huons - Tue Oct 04, 2005 10:47 pm

I have no history of kidney disease. My last CMP revealed creatinine 1.0, BUN 7, BUN/Creatinine 7. The estimated GFR is 65 mL/min/1.73sq.m. I am a 42 year old white woman with a weight of 156 pounds. My estimated GFR eight months ago was 73. Should I be concerned?
 Dr. Safaa Mahmoud - Sat Aug 26, 2006 5:53 pm

User avatar Hello,

Creatinine clearance normal range: 90–140 milliliters per minute (mL/min).

Low creatinine clearance indicate kidney damage. Kidney damage can reversible or chronic.

Chronic renal damage is diagnosed if the findings that support renal damage persists for more than 3 month after conservative measures.

Damage of the kidney is generally due to either reduced blood flow to the kidneys, or urinary tract blockage.

Indomethacin and NSAID are commonly used medications and can result in reversible renal damage in the majority of chronic users.

Measurement of creatinine clearance with 24-h urine collection is considered as an adequate estimate of GFR.

People with GFR above 60 cc/min are considered to have mild form or renal damage that warrants considering preventive measures that should be recommended by the nephrologist.

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