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Charcot -Marie -Tooth

This disease has the largest prevalence among hereditary neuropathies. Several genotypes exist.

Manifestations

Motor manifestations: Stork leg appearance and frequently distal upper limb atrophy.

Sensory manifestations: loss of sensation on the peroneal nerve distribution.

Sometimes a palpable hypertrophic neuropathy due to recurrent demyelination.

Treatment

Mainly supportive therapy and symptom care.  

 

 

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