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Olivopontocerebellar degeneration (OPCD)
A loose group of uncommon progressive degenerative disorders that cause
cerebellar dysfunction with or without other motor or sensory affection.
Pathologically the most common denominator in this category is degenerative
changes in the pons, olive and cerebellum.
The condition in the 40-60 (as early as 20) age group. There is no sexual
predilection. The condition is autosomal dominant.
Clinical suspicion
Patient presents with any combination of the following dysfunctions:
- Cerebellar dysfunctions
- Nystagmus
- Pyrmaidal tract lesions
- Parkinsonian signs
- Dementia
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Diagnosis
MRI shows degeneration in advanced cases.
Treatment
Is mainly symptomatic.
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