Name: Dicyclomine hydrochloride
Pregnancy Category C
Mechanisms of action
Direct GI smooth muscle relaxant; competitively blocks the effects of
acetylcholine at muscarinic cholinergic receptors that mediate the effects
of parasympathetic postganglionic impulses, thus relaxing the GI tract.
Treatment of functional bowel or irritable bowel syndrome (irritable
colon, spastic colon, mucous colitis)
Contraindicated in the presence of glaucoma; adhesions between iris and
lens, stenosing peptic ulcer, pyloroduodenal obstruction, paralytic ileus,
intestinal atony, severe ulcerative colitis, toxic megacolon, symptomatic
prostatic hypertrophy, bladder neck obstruction, bronchial asthma, COPD,
cardiac arrhythmias, tachycardia, myocardial ischemia; impaired metabolic,
liver, or kidney function, myasthenia gravis; lactation.
Use caution in the presence of Down's syndrome, brain damage, spasticity,