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Ipratropium bromide
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The FDA approved Xolair™, the first in a new class of asthma therapies that
are bioengineered to target IgE.
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Atrovent
Pregnancy Category B
Drug classes
Anticholinergic
Bronchodilator
Antimuscarinic
Parasympatholytic
Mechanism of action
Anticholinergic, chemically related to atropine, which blocks vagally
mediated reflexes by antagonizing the action of acetylcholine.
Indications
- Bronchodilator for maintenance treatment of bronchospasm associated
with COPD
Contraindications
- Hypersensitivity to atropine or its
derivatives
- Acute episodes of bronchospasm.
Use caution in the presence of narrow-angle glaucoma, prostatic hypertrophy,
bladder neck obstruction, pregnancy, lactation.

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Adverse effects
- CNS: Nervousness, dizziness, headache,
fatigue, insomnia, blurred vision
- GI: Nausea, GI distress, dry mouth
- Respiratory:
Cough, exacerbation of symptoms, hoarseness
- Other: Palpitations, rash
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