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Back to Drug index

Back to Anticholinergics

Ipratropium bromide

 

The FDA approved Xolair?, the first in a new class of asthma therapies that are bioengineered to target IgE.

 
 

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  Related
 
 

Asthma disease review

 
   
 
     

Atrovent

Pregnancy Category B

Drug classes

Anticholinergic
Bronchodilator
Antimuscarinic
Parasympatholytic

Mechanism of action

Anticholinergic, chemically related to atropine, which blocks vagally mediated reflexes by antagonizing the action of acetylcholine.

Indications

  1. Bronchodilator for maintenance treatment of bronchospasm associated with COPD

Contraindications

  1. Hypersensitivity to atropine or its
    derivatives
  2. Acute episodes of bronchospasm.

Use caution in the presence of narrow-angle glaucoma, prostatic hypertrophy, bladder neck obstruction, pregnancy, lactation.

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Adverse effects

  • CNS: Nervousness, dizziness, headache, fatigue, insomnia, blurred vision
  • GI: Nausea, GI distress, dry mouth
  • Respiratory: Cough, exacerbation of symptoms, hoarseness
  • Other: Palpitations, rash
 

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