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Name: Methylphenidate hydrochloride
Pregnancy Category C
C-II controlled substance
Mild cortical stimulant with CNS actions similar to those of the
amphetamines; efficacy in hyperkinetic syndrome, attention-deficit
disorders in children appears paradoxical and is not understood.
- Attention-deficit disorders, hyperkinetic syndrome, minimal brain
dysfunction in children with a behavioral syndrome characterized by
following symptoms: moderate to severe distractibility, short
span, hyperactivity, emotional lability and impulsivity, not secondary
environmental factors or psychiatric disorders
- Unlabeled use: treatment of depression in the elderly, cancer and
Contraindicated in the presence of hypersensitivity to
marked anxiety, tension, and agitation; glaucoma; motor tics, family
history or diagnosis of Gilles de la Tourette's syndrome; severe
depression of endogenous or exogenous origin; normal fatigue states.
Use caution in the presence of seizure disorders; hypertension; drug
dependence, alcoholism; emotional instability; lactation.
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- CNS: Nervousness, insomnia, dizziness, headache, dyskinesia, chorea,
drowsiness, Gilles de la Tourette's syndrome, toxic psychosis, blurred
vision, accommodation difficulties
- GI: Anorexia, nausea, abdominal pain, weight loss
- CV: Increased or decreased pulse and blood pressure; tachycardia,
angina, cardiac arrhythmias, palpitations
- Hematologic: Leukopenia, anemia
- Dermatologic: Skin rash, urticaria, fever, arthralgia, exfoliative
dermatitis, erythema multiforme with necrotizing vasculitis and
thrombocytopenic purpura, loss of scalp hair
- Other: Tolerance, psychological dependence, abnormal behavior with