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Back to Drug index
Name: Cyclobenzaprine hydrochloride
Pregnancy Category B
Drug classes
Centrally acting skeletal muscle relaxant
Therapeutic actions
Precise mechanism of action not known; does not directly relax tense
skeletal muscles but appears to act mainly at brain stem levels or in
the
spinal cord.
Indications
Relief of discomfort associated with acute, painful musculoskeletal
conditions, as an adjunct to rest, physical therapy
Unlabeled use: adjunct in the management of fibrositis syndrome
Contraindications/cautions
Contraindicated in the presence of hypersensistivity to
cyclobenzaprine,
acute recovery phase of myocardial infarction, arrhythmias, heart
block
or conduction disturbances, CHF, hyperthyroidism.
Use with caution in the presence of urinary retention, angle-closure
glaucoma, increased intraocular pressure, lactation.
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Adverse effects
- CNS: Drowsiness, dizziness, fatigue, tiredness, asthenia, blurred
vision, headache, nervousness, confusion
- GI: Dry mouth, nausea, constipation, dyspepsia, unpleasant taste,
liver
toxicity in preclinical studies
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