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Hodgkin's disease is a type of lymphoma described by Thomas Hodgkin in
1832, and characterized by the presence of Reed-Sternberg cells.
The estimated new cases and deaths from Hodgkin's lymphoma in the
United States in 2005 are:
New cases: 7,350
Due to the advances of therapy for Hodgkin's lymphoma over
the past 4 decades more than 75% of all newly diagnosed patients can
expect a disease-free normal life span.
It is slightly more common in males with a male-to-female
ratio of Hodgkin?s disease is 1.3 to 1.
Unlike other lymphomas, whose incidence increases with age,
Hodgkin's lymphoma has a bimodal incidence curve: that is, it occurs
more frequently in two separate age groups, the first being young
adulthood (age 15-35), the second being in those over 50 years old.
Race and ethnicity
Hodgkin?s disease occurs less commonly in African-Americans
(2.3 cases per 100,000 persons) than in Caucasians (3.0 per 100,000
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The age-specific incidence of Hodgkin?s disease differs
markedly in different countries. In Japan, the overall incidence is low
and the early peak is absent. In some developing countries, there is a
downward shift of the first peak into childhood.