Back to Oncology Diseases
Updated: October 29, 2005
Hepatocellular carcinoma is a primary malignancy of the liver. The
annual is around 5 cases per 100,000 per year. Estimated new cases
and deaths from liver and intrahepatic bile duct cancer in the
United States in 2005:
- New cases: 17,550.
- Deaths: 15,420.
A study analyzing SEER (Surveillance, Epidemiology, and End
Results) data has shown that the incidence of hepatocellular
carcinoma is rising in both white and black populations in the
United States, with a current incidence of about 3.4 cases per
100,000 in whites and 5.6 per 100,000 in blacks.
Hepatocellular carcinoma is the most common tumor in males
worldwide, with a male-to-female ratio of 5:1 in Asia and 2:1 in the
The incidence of hepatocellular cancer increases with age. The
mean age at diagnosis is 53 years in Asia and 67 years in the United
Race and ethnicity
The incidence of hepatocellular tumors is higher in
Asian immigrants and blacks than in whites.
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Tumor incidence varies significantly, depending on
geographical location. In the Far East and sub- Saharan Africa, this
neoplasm occurs at an incidence of 150 per 100,000 population and
comprises almost 50% of all diagnosed tumors, whereas in the United
States, hepatocellular carcinoma represents < 2% of all tumors.