Back to Oncology Diseases

Non-Hodgkin's Lymphoma
Introduction

 

  Non-Hodgkin's Lymphoma News

 
 
 

tellfrnd.gif (30x26 -- 1330 bytes)send to a friend
 
prntfrnd.gif (30x26 -- 1309 bytes)printer friendly version
 
    Non-Hodgkin's Lymphoma
 
   

Non-Hodgkin's lymphomas (NHLs) are in fact a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment.

Incidence

Estimated new cases and deaths from non-Hodgkin's lymphoma (NHL) in the United States in 2005:

  • New cases: 56,390.
  • Deaths: 19,200.

In the United States, the incidence has increased from 6.9 per 100,000 population in 1947 to 1950 to 17.4 per 100,000 population in 1984 to 1988.

Gender

Male : female ratio is about 1.5:1.

Age

Except for high-grade lymphoblastic and Burkitt lymphomas (the most common types of NHL seen in children and young adults), the median age at presentation for all subtypes of NHL exceeds 50+ years. Low-grade lymphomas account for 37% of NHLs in patients between the ages of 35 and 64 years at diagnosis but for only 16% of cases in those younger than age 35.

Race and ethnicity

Incidence varies by race, with whites at higher risk than blacks and Asian-Americans. Most histologies, particularly low-grade small lymphocytic and follicular lymphomas, are more common in whites than blacks. The incidence of mycosis fungoides and other peripheral T-cell lymphomas is higher in black males and lowest in white females.

Geography

Certain endemic geographic factors appear to influence the development of NHL in specific areas:

  • Burkitt lymphoma in Africa
  • Immunoproliferative small intestinal disease (α−chain disease) is rarely encountered in individuals other than those of Mediterranean ethnic origin.
  • Human T-cell lymphotrophic virus-1 (HTLV-1)?associated T-cell lymphoma/leukemia occurs more frequently in Japan (Kyushu) and the Caribbean.
  • Peripheral T-cell lymphomas are more common in Europe and China than in North America.
  • Follicular lymphomas are more common in North America and Europe but are rare in the Caribbean, Africa, China, Japan, and the Middle East.
previous.gif (72x17 -- 347 bytes) next.gif (72x17 -- 277 bytes)

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us