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Ovarian cancer is a malignant neoplasm (abnormal growth) located on
Age Ovarian cancer is primarily a disease of postmenopausal
women, with the
large majority of cases occurring in women between 50 and 75 years
incidence of ovarian cancer increases with age and peaks at a rate
of 61.5 per
100,000 women in the 75?79-year-old age group.
Race The incidence of ovarian cancer appears to vary by race,
effects of race are difficult to separate from those of environment
culture, geography, and socioeconomic status. In the United States,
rate of ovarian cancer for Caucasians is estimated to be 17.9 per
population, which is significantly higher than 11.9 per 100,000 for
Geography There are distinct geographic variations in the incidence
cancer, with the highest rates found in the industrialized countries
lowest rates seen in underdeveloped nations. Japan, with an
incidence of only
about 3.0 per 100,000 population, is a notable exception to this
has been postulated that geographic variations in the incidence of
cer are related, in part, to differences in family size.
Some of the highest rates are seen in women of Eastern European
who have an estimated incidence of 17.2 per 100,000 population, a
probable result of the relatively high frequency of BRCA1 and BRCA2
in this population.
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