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Back to Oncology Diseases
Pancreatic cancer
Introduction
Incidence
Pancreatic cancer occurs at an incidence of approximately 10 per
100,000 per year. Due to the aggressiveness of this tumor and
difficult early diagnosis the mortality rate is virtually equal to the
incidence (10 per 100,000).
Pancreatic cancer is the fifth leading cause of cancer-related
death for both men and women (following lung, colon, breast, and
prostate cancers) and is responsible for 5% of all cancer-related
deaths.
Estimated new cases and deaths from pancreatic cancer in the United
States in 2005:
- New cases: 32,180.
- Deaths: 31,800.
Gender
Pancreatic cancer is slightly higher in males than in females
especially in younger populations.
Age
The disease incidence peaks between the age of 67 and 79 and is
rare below the age of 40.
Race and ethnicity
Blacks are more at risk than whites (50% excess risk). Black
males have the highest incidence of pancreatic cancer worldwide.
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Geography
Pancreatic cancer incidence and mortality statistics are similar
throughout the world. The reasons for the slight regional and ethnic
differences in the incidence of pancreatic cancer are unknown, but
this may be due to a trend toward a decline in tobacco use in
certain groups and regions. Incidence rates are highest in
industrialized societies and western countries. In Japan, cigarette
smoking carries an even greater risk, which can be as much as
10-fold in men smoking one to two packs of cigarettes daily.
- In Europe, rates are highest in the Nordic countries.
- In the United States, rates are particularly high in native
Hawaiians, African Americans, and Korean Americans, with the
highest rates in African Americans. The fact that the rates in
African Americans are considerably higher than in native
Africans suggests an environmental influence.
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