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Forum Name: Liver Cancer

Question: Liver Cancer/Cirrhosis


 Mrs2U - Fri Dec 22, 2006 12:34 pm

My mother, age 66, recently finished chemo for acute leukemia in May '06. She has cirhhosis, and that condition complicated her treatment greatly. Recently she has not felt well, lost weight, etc, so we scheduled her to see a gastro for a visit. Her last CT liver scan was done in 2005. Apparently, there have been some changes to her liver. The doctor said there are new areas of attenuation, although the report indicated they are nonspecific. The gastro. said that liver cancer is a real possibility, and she is scheduled for an MRI. She has not drank in several years, but I'm wondering if perhaps the chemo drugs could have caused the differences in her CT scan compared with 2005. What is the prognosis of liver cancer?

Thank you for any information.
 Dr. Safaa Mahmoud - Sat Dec 23, 2006 9:27 am

User avatar Hello,


It would be more helpful if you could inform us about the details written in her report for the CT scan.

It is very difficult to differentiate between liver cirrhosis lesion from malignant ones by conventional US or CT scan. Major difficulties occur when the liver parenchyma is not homogeneous (cirrhosis ) and the lesions are smaller than 1 cm.

New techniques like the Triple-phase, high-resolution CT and contrast-enhanced MRI are now the primary imaging modalities in the diagnosis and to stage liver carcinoma HCC.

The prognosis of patients with HCC depends on a group of factors including the extent of the disease in the liver, liver condition and the general condition of the patients including an existing comorbid condition.

Improved survival is seen when curative resection is possible, small tumor size, well-differentiated tumors, and normal performance status.

The 5-year survival rate in patients undergo curative resection,
can reach 20%.

Keep us updated.
Best regards.

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