|
|
| |
|
Headlines:
|
 |
|
| |
Doctors Lounge - Oncology Answers
"The information
provided on www.doctorslounge.com is designed to support, not
replace, the relationship that exists between a patient/site
visitor and his/her physician."
Back to Oncology Answers List
| bhasaji
- Sun Sep 06, 2009 4:39 am |
|
My father had CLL at 46 years age, and he passed at 57 years in 2005. Recently, I discovered that his aunt ( real sister of his mother) also has CLL and she is 72 years.
Is is a familial CLL? Could it be? Is there any way I can find if I am predisposed to developing CLL? I am 37 years male.
Sister of my father has also developed Ca Breast recently.
ANy response is highly appreciated
|
| Dr. Tamer Fouad
- Sun Sep 06, 2009 8:11 am |
|
 Hello,
First degree relatives of CLL patients have been found in some studies to have a higher risk of CLL as well as other tumors a phenomenon referred to as familial aggregation. Although this disease is not hereditary and there is no evidence of genetic transmission. It may be that certain genes that run in a family make it more likely for family members to develop these tumors.
Although, there aren't any formal guidelines for special screening of family members of CLL patients, it would be a good idea to let your family doctor / Aunt's doctor know of your concern.
I am throwing in a few references for convenience.
REFERENCES:
===========
1. Cuttner, J. Increased incidence of hematologic malignancies in first-degree relatives of patients with chronic lymphocytic leukemia. Cancer Invest 1992;10(2):103-9.
2. Yuille MR; Matutes E; Marossy A; Hilditch B; Catovsky D; Houlston RS. Familial chronic lymphocytic leukaemia: a survey and review of published studies. Br J Haematol 2000 Jun;109(4):794-9.
3. Brown JR; Neuberg D; Phillips K; Reynolds H et al. Prevalence of familial malignancy in a prospectively screened cohort of patients with lymphoproliferative disorders. Br J Haematol. 2008 Nov;143(3):361-8. Epub 2008 Aug 20.
|
|
|
|
|
|
Are you a Doctor, Pharmacist, PA or a Nurse?
Join the Doctors Lounge online medical community
-
Editorial activities: Publish, peer review, edit
online articles.
-
Ask a Doctor Teams: Respond to patient questions and
discuss challenging presentations with other members.
Doctors Lounge Membership
Application |
|
|
|
| |
|
|
|
|
