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Forum Name: Lymphoma

Question: Lymphomatoid Papulosis


 lillylilly - Thu Aug 19, 2010 7:10 pm

Is the only way to diagnose lymphomatoid papulosis through a biopsy of an eruption, and if so, does the biopsy have to be taken during a certain phase of the eruption in order to show positive results for the disease? Thank you.
 Dr.M.jagesh kamath - Sun Aug 22, 2010 10:34 am

User avatar Hello,The diagnosis of this peculiar condition showing atypical lymphocytes with CD30 positivity resembling lympho proliferative tumors yet with self limiting course with good prognosis,is indeed a very interesting condition.Type A the histocytic type Type B the lymphocytic type,type c the anaplastic type could only be differentiated by histopathology and immuno histochemistry and phenotype studies.This disease has a malignant look on histopathology but benign course clinically.The disease would show up as mildly itchy papules on the trunk which disappear in a month or two leaving behind a depressed scar.Cause is not known.Oral psoralens with ultraviolet light(PUVA) is the gold standard in therapy.
Best wishes.

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