AF                                                     bladder(8)
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  adriamycin...... 50 mg/sqm IV day 1.
  fluorouracil.... 600 mg/sqm IV day 1.
  FREQUENCY....... Repeat cycle every 3 weeks.

  reference...
    Martino S.  Samal B.  Al-Sarraf M. Phase II study of 
    5-fluorouracil and adriamycin in transitional cell carcinoma 
    of the urinary tract. Cancer Treatment Reports.  64(1):161-3, 
    1980 Jan. 
  abstract...
    A prospective study was carried out to determine the 
    effectiveness and tolerance of the combination of 
    5-fluorouracil (600 mg/m2) and Adriamycin (50 mg/m2) given iv 
    every 3 weeks to patients with disseminated transitional cell 
    carcinoma of the urinary tract. Twenty-one of 23 patients 
    entered in the study were evaluable for both response and 
    toxicity. Two patients had complete responses and six had 
    partial responses (greater than or equal to 50% reduction), 
    yielding an overall response rate (complete plus partial) of 
    38%. Leukopenia (72.7%) and thrombocytopenia (54.5%) were 
    common. Toxicity was life-threatening in one patient. Other 
    common side effects were alopecia, nausea and vomiting, and a 
    generalized feeling of weakness. Responders had a median 
    survival time of 29 weeks compared to a median survival time 
    of 9 weeks for nonresponders.