Advertisement
 

doctorslounge.com

 
Powered by
Careerbuilder

 

                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Ask a Doctor

   News via RSS

   Newsletter

   Oncology

   News

 

 Conferences


   CME

   Forum Archives

   Diseases

   Symptoms

   Labs

   Procedures

   Drugs

   Links
   Specialties

   Cardiology

   Dermatology

   Endocrinology

   Fertility

   Gastroenterology

   Gynecology

   Hematology

   Infections

   Nephrology

   Neurology

   Oncology

   Orthopedics

   Pediatrics

   Pharmacy

   Primary Care

   Psychiatry

   Pulmonology

   Rheumatology

   Surgery

   Urology

   Other Sections

   Membership

   Research Tools

   Medical Tutorials

   Medical Software

 

 Headlines:

 
 

Back to index

Cancer Chemotherapy Regimen for Breast Cancer


 COOPER                                                 breast(24)
 _________________________________________________________________
  fluorouracil.... 12 mg/kg IV every week times 8 weeks, then 
                   every other week for 7 additional months.
  methotrexate.... 0.7 mg/kg/week IV times 8 weeks, then every 
                   other week for 7 months.
  vincristine..... 0.035 mg/kg/week IV times 5 weeks, then once 
                   monthly.
  cytoxan......... 2 mg/kg/day orally times 9 months.
  prednisone...... 0.75 mg/kg/day orally times 10 days, then one 
                   half times 10 days, then one fourth times 10 
                   days, then 5 mg/day times 20 days, and then 
                   discontinue.
  FREQUENCY....... Specified with the drugs above.

  reference...
    Cooper RG.  Holland JF.  Glidewell O. Adjuvant chemotherapy of 
    breast cancer. Cancer.  44(3):793-8, 1979 Sep. 
  abstract...
    One hundred women with primary breast cancer with 4 or more 
    metastatic axillary nodes were treated for 9 months 
    postoperatively with vincristine, prednisone, 
    cyclophosphamide, methotrexate, and fluorouracil (VPCMF). 
    Sixty-five women have been observed for a minimum of 5 years 
    or until failure and the rest for 3 years or more. For 73 
    women who received adjuvant chemotherapy only, observed for 5 
    1/2 years median, disease-free status by life table analysis 
    is 68% at 8 years. No significance difference was found 
    between response of pre- and postmenopausal women in 
    disease-free interval or survival. Mortality compared to 
    expectation was sharply reduced; only 9 of 73 have died. These 
    findings demonstrate the long term effectiveness of relatively 
    short-term surgical adjuvant combination chemotherapy in pre- 
    and post-menopausal patients with breast cancer at high risk. 
advertisement.gif (61x7 -- 0 bytes)
 

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application



 

 advertisement.gif (61x7 -- 0 bytes)

 

 

 



We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright 2001-2012 DoctorsLounge. All rights reserved.