L-FAC breast(147)
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leucovorin...... 200 mg/sqm IV over 30 min on days 1, 2, and 3.
fluorouracil.... 400 mg/sqm IV continuous on days 1, 2, and 3.
adriamycin...... 30 mg/sqm IV continuous on days 1, and 2.
cytoxan......... 750 mg/sqm IV over 24 h on day 1.
FREQUENCY....... Repeat course every 11 to 18 days, depending on
toxicity.
147. Jabboury K, Rogers L, Loh A, Mangini O. Complete
pathological remission in breast cancer: An early frequent
finding with dose-intensification L-FAC, leucovorin (L),
fluorouracil (F), doxorubicin (A), and cyclophosphamide (C).
Proc Am Soc Clin Oncol 14:131, 1995.
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