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Cancer Chemotherapy Regimen for Carcinoid Cancer


 SF                                                  carcinoid(39)
 _________________________________________________________________
  streptozotocin.. 500 mg/sqm/day IV days 1 to 5.
  fluorouracil.... 500 mg/sqm/day IV days 1 to 5.
  FREQUENCY....... Repeat cycle every 28 days.

  reference...
    Chernicoff D.  Bukowski RM.  Groppe CW Jr.  Hewlett JS. 
    Combination chemotherapy for islet cell carcinoma and 
    metastatic carcinoid tumors with 5-fluorouracil and 
    streptozotocin. Cancer Treatment Reports.  63(5):795-6, 1979 
    May. 
  abstract...
    The results of combination chemotherapy with intermittent 
    courses of 5-fluorouracil and streptozotocin in ten patients 
    with metastatic carcinoid tumors and in eight patients with 
    islet cell carcinoma are reported. Objective responses 
    occurred in two of ten and in two of seven evaluable patients 
    respectively. Biochemical responses occurred in an additional 
    two patients with carcinoid. No improvement over single-agent 
    chemotherapy and no effects on survival were noted. 
 
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