CVB                                                 esophagus(53)
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  cisplatin....... 3 mg/kg or 120 mg/sqm (whichever is less) IV 
                   day 1.
  vindesine....... 3 mg/sqm IV on days 1, 8, 15, and 22.
  bleomycin....... 10 U/sqm IV (loading dose) on day 1; then 10 
                   U/sqm/day by continuous IV on days 3 to 6.
  FREQUENCY....... Repeat above regimen once at four weeks. 
                   Thereafter, discontinue bleomycin, and 
                   administer vindesine every 2 weeks and 
                   cisplatin every 6 weeks.

  reference...
    Kelsen DP.  Bains M.  Hilaris B.  Chapman R.  McCormack P.  
    Alexander J. Hopfan S.  Martini N. Combination chemotherapy of 
    esophageal carcinoma using cisplatin, vindesine, and 
    bleomycin. Cancer.  49(6):1174-7, 1982 Mar 15. 
  abstract...
    Sixty-one patients with epidermoid carcinoma of the esophagus 
    have been treated with a three drug combination of cisplatin, 
    vindesine, and bleomycin. Of 53 patients currently evaluable 
    for response, 29 (55%) have had partial remissions: 7/16 with 
    metastatic, and 22/37 with local-regional disease. The median 
    duration of response in metastatic patients is eight months. 
    Of 28 patients treated preoperatively, 23 (82%) had resectable 
    disease. The major toxicities seen were nephrotoxicity and 
    myelosuppression. Cisplatin, vindesine and bleomycin is an 
    effective combination in the treatment of esophageal 
    carcinoma. Effects on long-term survival cannot yet be 
    evaluated.