Cancer Chemotherapy Regimen for Non-small Cell Lung Cancer
CAMP _________________________________________________________________ cytoxan......... 300 mg/sqm IV on days 1 and 8. adriamycin...... 20 mg/sqm IV on days 1 and 8. methotrexate.... 15 mg/sqm IV on days 1 and 8. procarbazine.... 100 mg/day orally for 10 days. FREQUENCY....... Repeat cycle every 28 days. reference... Bitran JD. Desser RK. DeMeester TR. Colman M. Evans R. Billings A. Griem M. Rubenstein L. Shapiro C. Golomb HM. Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma. Cancer Treatment Reports. 60(9):1225-30, 1976 Sep. abstract... Twenty-three patients with metastatic non-oat cell bronchogenic carcinoma (MNOBC) were treated with cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) after radiation therapy. Objective responses were seen in 11 of 23 patients (48%) with a projected median survival time of 12.5 months for responding patients and patients with stable disease. Lung, liver, and cutaneous sites of involvement proved to be highly responsive; bone involvement was less responsive. CAMP is an effective combination in the treatment of MNOBC and its use in patients with less advanced disease should be explored.
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