SALVAGE lymphoma(100)
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prednisone...... 80 mg/sqm/day orally from day 1 to day 5.
cytarabine...... 100 mg/sqm/day SC from day 1 to day 5.
lomustine....... 40 mg/sqm orally day 1.
FREQUENCY....... Repeat cycle every 2 months for a maximum of
six courses.
reference...
Ng PR. Todd D. Khoo RK. Salvage chemotherapy for
non-Hodgkin's lymphoma. Cancer Treatment Reports.
66(11):1977-9, 1982 Nov.
abstract...
Nineteen patients with advanced non-Hodgkin's lymphoma
resistant to previous chemotherapy were treated with
combination chemotherapy consisting of lomustine (CCNU),
cytarabine, and prednisone. Eight patients (42%) had complete
remission and four (21%) had partial remission. The median
survival time of the 19 patients was greater than 14 months.
The eight patients who had complete remission were still alive
as of May 1, 1982, with a median follow-up time of 632 days
(range, 365-1247). We believe that this combination
chemotherapy scheme warrants further investigation.
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