FAP-RAD pancreas(123)
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fluorouracil.... 300 mg/sqm/day IV from day 1 to day 5.
[500 mg/sqm/day IV from day 1 to day 3 during
each course of radiation therapy].
adriamycin...... 50 mg/sqm IV day 1.
cisplatin....... 20 mg/sqm/day IV from day 1 to day 5.
radiation....... After 6 cycles of chemotherapy, irradiate at
200 rad/day; 5 days/week for 2 weeks, rest for
2 weeks, then repeat radiation as described.
FREQUENCY....... Repeat chemotherapy every 21 days for 6 cycles,
then administer combined fluorouracil
chemotherapy and irradiation.
123. Wagener D, vanHoesel Q, Hoogenraad W, et.al. A phase 2 study
of 5-FU, adriamycin and cisplatin (FAP) followed by a split
course of radiation in combination with 5-FU for locally
advanced pancreatic cancer. Proc Am Soc Clin Oncol 6:77,
1987.
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