Advertisement
 

doctorslounge.com

 
Powered by
Careerbuilder

 

                    Home  |  Forums  |  Humor  |  Advertising  |  Contact
   Ask a Doctor

   News via RSS

   Newsletter

   Oncology

   News

 

 Conferences


   CME

   Forum Archives

   Diseases

   Symptoms

   Labs

   Procedures

   Drugs

   Links
   Specialties

   Cardiology

   Dermatology

   Endocrinology

   Fertility

   Gastroenterology

   Gynecology

   Hematology

   Infections

   Nephrology

   Neurology

   Oncology

   Orthopedics

   Pediatrics

   Pharmacy

   Primary Care

   Psychiatry

   Pulmonology

   Rheumatology

   Surgery

   Urology

   Other Sections

   Membership

   Research Tools

   Medical Tutorials

   Medical Software

 

 Headlines:

 
 

Back to cancer staging index

Cancer Staging Systems

Staging of Malignant Melanoma

Last Update: Sunday January 4th, 2004 7:15 PM GMT

Clark?s classification (level of invasion)

  • Level I: Lesions involving only the epidermis (in situ melanoma); not an invasive lesion.
  • Level II: Invasion of the papillary dermis, but does not reach the papillary-reticular dermal interface.
  • Level III: Invasion fills and expands the papillary dermis, but does not penetrate the reticular dermis.
  • Level IV: Invasion into the reticular dermis but not into the subcutaneous tissue.
  • Level V: Invasion through the reticular dermis into the subcutaneous tissue.

TNM Definition

Primary tumor (T)

  • TX: Primary tumor cannot be assessed (e.g., shave biopsy or regressed melanoma)
  • T0: No evidence of primary tumor
  • Tis: Melanoma in situ
  • T1: Tumor 1.0 mm or less in thickness with or without ulceration
    • T1a: Tumor 1.0 mm or less in thickness and Clark?s level II or III, no ulceration
    • T1b: Tumor 1.0 mm or less in thickness and Clark?s level IV or V or with ulceration
  • T2: Tumor more than 1.0 mm but not more than 2.0 mm in thickness with or without ulceration
    • T2a: Tumor more than 1.0 mm but not more than 2.0 mm in thickness, no ulceration
    • T2b: Tumor more than 1.0 mm but not more than 2.0 mm in thickness, with ulceration
  • T3: Tumor more than 2.0 mm but not more than 4 mm in thickness with or without ulceration
    • T3a: Tumor more than 2.0 mm but not more than 4 mm in thickness, no ulceration
    • T3b: Tumor more than 2.0 mm but not more than 4 mm in thickness, with ulceration
  • T4: Tumor more than 4.0 mm in thickness with or without ulceration
    • T4a: Tumor more than 4.0 mm in thickness, no ulceration
    • T4b: Tumor more than 4.0 mm in thickness, with ulceration

Regional lymph nodes (N)

  • NX: Regional lymph nodes cannot be assessed
  • N0: No regional lymph node metastasis
  • N1: Metastasis to 1 lymph node
    • N1a: Clinically occult (microscopic) metastasis
    • N1b: Clinically apparent (macroscopic) metastasis
  • N2: Metastasis to 2 or 3 regional nodes or intralymphatic regional metastasis without nodal metastases
    • N2a: Clinically occult (microscopic) metastasis
    • N2b: Clinically apparent (macroscopic) metastasis
    • N2c: Satellite or in-transit metastasis without nodal metastasis
  • N3: Metastasis in 4 or more regional nodes, or matted lymph nodes, or in-transit metastasis or satellite(s) with metastatic regional node(s)

Distant Metastasis (M)

  • MX: Distant metastasis cannot be assessed
  • M0: No distant metastasis
  • M1: Distant metastasis
    • M1a: Metastasis to skin, subcutaneous tissues, or distant lymph nodes
    • M1b: Metastasis to lung
    • M1c: Metastasis to all other visceral sites or distant metastasis at any site associated with an elevated serum lactic dehydrogenase (LDH)
advertisement.gif (61x7 -- 0 bytes)
 

Are you a doctor or a nurse?

Do you want to join the Doctors Lounge online medical community?

Participate in editorial activities (publish, peer review, edit) and give a helping hand to the largest online community of patients.

Click on the link below to see the requirements:

Doctors Lounge Membership Application


Stage grouping

Stage 0

  • Tis, N0, M0

Stage IA

  • T1a, N0, M0

Stage IB

  • T1b, N0, M0
  • T2a, N0, M0

Stage IIA

  • T2b, N0, M0
  • T3a, N0, M0

Stage IIB

  • T3b, N0, M0
  • T4a, N0, M0

Stage IIC

  • T4b, N0, M0

Stage III

  • Any T, N1, M0
  • Any T, N2, M0
  • Any T, N3, M0

Stage IV

  • Any T, any N, M1

References

  1. Melanoma of the skin. In: American Joint Committee on Cancer.: AJCC Cancer Staging Manual. 6th ed. New York, NY: Springer, 2002, pp 209-220.
 

 advertisement.gif (61x7 -- 0 bytes)

 

 



We subscribe to the HONcode principles of the HON Foundation. Click to verify.
We subscribe to the HONcode principles. Verify here

Privacy Statement | Terms & Conditions | Editorial Board | About us
Copyright 2001-2012 DoctorsLounge. All rights reserved.