News  |  Journals  |  Conferences  |  Blogs  |  Articles  |  Forums  |  Twitter   

Doctors Lounge - Pediatrics Answers

"The information provided on is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician."

Back to Pediatrics Answers List

Forum Name: Pediatric Topics

Question: Rett syndrome

 jordan*joeysmom - Mon May 10, 2004 10:12 pm

I have a cousin my age, 23, with rett syndrome. Is this a syndrome that "runs in the family"?
 Dr. Tamer Fouad - Tue May 11, 2004 3:57 pm

User avatar Rett syndrome is caused by a mutation in a certain gene called the MECP2 gene. However, mutations in MECP2 are almost always sporadic, that is, they occur spontaneously rather than through heredity. That means that parents rarely pass on the disease to their children. Even if a child does inherit the mutation, however, boys don’t usually get RS. That’s because the father can’t pass it on to them. In order for the fetus to become a boy, the father must pass on a Y chromosome, not an X chromosome. Since the MECP2 gene is located only on the X chromosome, the boy, by virtue of being XY, avoids RS.

No they don't run in families.

| Check a doctor's response to similar questions
advertisement.gif (61x7 -- 0 bytes)

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application



Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us

Copyright © 2001-2017
Doctors Lounge.
All rights reserved.

Medical Reference:
Diseases | Symptoms
Drugs | Labs | Procedures
Software | Tutorials

Links | Humor
Forum Archive
CME Articles

Privacy Statement
Terms & Conditions
Editorial Board
About us | Email

We subscribe to the HONcode principles of the HON Foundation. Click to verify.We subscribe to the HONcode principles.
Verify here