The Doctors Lounge - Primary Care Answers
"The information provided
on www.doctorslounge.com is designed to support, not replace, the
relationship that exists between a patient/site visitor and his/her
physician."
Back to
Primary Care Answers List
Question: henoch-schoenlein
| Anonymous
- Fri May 02, 2003 4:29 pm |
Im doing a report for a physio class and was wondering if anyone could tell me how immunoglobulin A is responsible for the onset of Henoch-Schoenlein purpura. Thanks! :)
|
| a_medico
- Sat May 03, 2003 1:15 am |
Allergen(drugs,
food,
insect bite,
intection,
vaccination etc)##> stimulation##>elevated IgA levels -> IgA-mediated vasculitis in small vessels of involved organs -> necrotizing vasculitis##>HENOCH-SCHOENLEIN PURPURA
Mechanism of vasulitis:-
*deposition of IgA-containing immune complexes with subsequent activation of complement leads to a vasculitis
*biopsy of an acute skin lesion reveals an aseptic vasculitis with fibrinoid necrosis of vessel walls and perivascular cuffing of vessels
|
Check a doctor's response to similar questions
 send
to a friend
|
