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Back to Drug index
Name: Fat emulsion
Pregnancy Category C
Drug classes
Therapeutic actions
A preparation from soybean or safflower oil that provides neutral
triglycerides, mostly unsaturated fatty acids; these are used as a
source
of energy, causing an increase in heat production, decrease in
respiratory quotient, and increase in oxygen consumption.
Indications
- Source of calories and essential fatty acids for patients requiring
parental nutrition for extended periods
- Source of essential fatty acids when a deficiency occurs
Contraindications/cautions
- Contraindicated in the presence of disturbance of normal fat
metabolism
(hyperlipemia, lipoid nephrosis, acute pancreatitis), allergy to eggs.
- Use caution in the presence of severe liver damage, pulmonary disease,
anemia, blood coagulation disorders, pregnancy, jaundiced or premature
infants.
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Adverse effects
- CNS: Headache, flushing, fever, sweating, sleepiness, pressure over
the
eyes, dizziness
GI: Nausea, vomiting
- Hematologic: Thrombophlebitis, sepsis, hyperlipemia,
hypercoagulability,
thrombocytopenia, leukopenia, elevated liver enzymes
- Other: Irritation at infusion site, brown pigmentation in RES (IV fat
pigment), cyanosis
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