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Back to Psychiatry Drug Index

Back to Serotinine Reuptake Inhibitors

Brand Name: Effexor XR
Name: Venlafaxine

Pregnancy Category C

Drug classes of Effexor

Mechanism of action of Effexor

Acts as an antidepressant by inhibiting CNS neuronal uptake of serotonin; blocks uptake of serotonin and norepinephrine with a weak inhibitory effect on dopamine reuptake.

Indications of Effexor

Treatment of depression and generalized anxiety disorder.

Contraindications of Effexor

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Adverse Reactionsof Effexor

  • CNS: Headache, somnolence, dizziness, insomnia, nervousness.
  • GIT: Nausea, xerostomia, constipation, anorexia.
  • Genitourinary: Abnormal ejaculation / orgasm.
  • Neuromuscular & skeletal: weakness.
  • Other: diaphoresis

Overdosage of Effexor

Toxicity from the drug is not lethal & can be tolerated with supportive therapy.


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