Back to Cardiovascular Diseases

Premature ventricular complexes (PVCs)

Premature ventricular complexes (PVCs) result from depolarizations that originate from the ventricles and occur prior to the next normally conducted sinus beat. PVCs often occur in the absence of structural heart disease and are increasingly frequent with age. Potential triggers are similar to those for PACs (smoking, alcohol, adrenergic stimuation).

ECG readings

The EGG reveals a premature QRS complex with a bizarre morphology typically greater than 120 milliseconds in duration, with a T-wave polarity opposite to that of the QRS complex.


PVCs typically require no therapy. When patients are symptomatic, therapy should be directed toward correction of underlying abnormalities. Specific antiarrhythmic agents may be effective in suppressing PVCs, but adverse effects (e.g., arrhythmia aggravation, proarrhythmia, death) preclude their widespread use. In the setting of acute myocacardial ischemia or infarction, IV lidocaine may suppress PVCs, but toxic effects (e.g., increased risk of asystole and CNS effects) appear to outweigh potential benefits in most cases.

previous.gif (72x17 -- 347 bytes) next.gif (72x17 -- 277 bytes)

Are you a Doctor, Pharmacist, PA or a Nurse?

Join the Doctors Lounge online medical community

  • Editorial activities: Publish, peer review, edit online articles.

  • Ask a Doctor Teams: Respond to patient questions and discuss challenging presentations with other members.

Doctors Lounge Membership Application

Tools & Services: Follow DoctorsLounge on Twitter Follow us on Twitter | RSS News | Newsletter | Contact us