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Date of last update: 10/20/2017.

Forum Name: Hypertension

Question: what can be used to come off of Zanaflex?

 Brian1976 - Tue Sep 16, 2008 10:11 pm

What would be used to help someone stop taking Zanaflex, but keep them from having a extremely fast heart rate and high blood pressure?
 John Kenyon, CNA - Fri Oct 03, 2008 10:44 pm

User avatar Hello -

The literature and common practice both dictate that Zanaflex (tizanidine) be discontinued by tapering off the drug gradually over a period of one to two weeks. While there may be some rebound effect if it has been taken on a regular basis for a considerable period of time, gradual reduction of the dose will usually prevent any significant rebound effect. There is no replacement or step-down drug, just tapering, which is often easier with the tablet form rather than capsules, but if capsule dosage is relatively high it can be halved, and then, if necessary, one's doctor can prescribe a lower dose to continue the tapering at a lower dose.

I hope this is helpful to you.

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