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Date of last update: 10/20/2017.

Forum Name: Valvular Heart Diseases

Question: Aortic reguritation

 luna16 - Thu May 05, 2005 8:32 pm

I am a 45 year old woman. I'm 5'3 and weigh 175 lbs. I have three children.

I took fen-phen in 1997 and became pregnant later that year. After I had my last son I decided to get an echo and be sure I didn't have any heart damage from the medication.

My first echo was done in January of 1999.

Here are my first echo results:
Lt. Atrium (End Diastole) - 3.2
Aortic Root (End Diastole) - 2.8
Rt. Ventricle (End Diastole) - 1.7
Lt. Ventricle (End Diastole) - 4.0
Lt. Ventricle (End Systole) - 2.7
Interventricular septum (End Diastole) - 1.1
Left Ventricular Posterior Wall (End Diastole) n/a

No structural valvular abnormalities are evident by echocardiographic imaging.

Left ventricular size and contractuality are within normal limits. Regional wall motion abnormalities are not detected. Left ventricular wall thickness appears to be normal. The ejection fraction is estimated as 65-70%.

No abnormality of chamber size or function is noted. There is no pericardian effusion.

CARDIAC DOPPLER: Color-flow cardiac doppler mapping as well as pulsed and continuous wave doppler interrogations were performed.

Trival pulmonary insufficiency is a normal variant.

Mild tricuspid regurgitation is a normal variant. Evidence of significant pulmonary hypertension is not noted. No other significant flow abnormality is noted. Conclusion: No abnormalities noted.

Several of my friends also took this diet drug and they urged me, a couple of years later, to contact a lawyer about the class action lawsuit that was being brought against the drug company. I did so and I was given another echo in August of 2002.

The second echo results are:

LV EDD - 49
LV ESD - 35
ISV D - 7
LVPW D - 11
RV EDD - 33
AR ROOT - 27
LA 34/36
LA/SI - 46
Ejection Fraction (>60%) 63
Technical quality: Good
LV Function/Wall Motion - WNL
Pulmonary Artery Pressure - 26 mmhg

Findings and Conclusions:
Mitral Reguritation - None
Aortic Reguritation - 32% Moderate
Ejection Fraction - greater than 60%
Left Atrium - Normal
Pulmonary Artery Pressure - Normal
Other comments: Trival TR

I obviously have little idea of what these things mean, but having the aortic reguritation go from "Mild" in my first echo to "Moderate" in my second is somewhat alarming.

My main questions: Should I be worried? Do I need to see a cardiologist and have this condition monitored?

I am the sort of person who can literally make myself sick from worrying about things like this. I had forgotten about these medical reports until I ran across them a few days ago. I feel stupid going to my family doctor with this stuff.

Thank you so much in advance for any information you can give me.
 Dr. Yasser Mokhtar - Thu May 19, 2005 10:39 pm

User avatar Dear Luna16,

The valvular regurgitation caused by phen-fen is reversible in the vast majority of the cases. It should start with moderate and then go to mild and not the opposite. i don't think that the effect of the phen-fen combination can last for 5 years before it starts showing a heart effect.

i suggest that you see a cardiologist regarding your aortic regurgitation to have an opinion regarding the aortic regurgitation.

Thank you very much for using our website and i hope that this information helped.

Yasser Mokhtar, M.D.

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