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Back to Antihistamines

Brand Name: Antihist-1
Name: Clemastine

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Pregnancy Category B

Drug classes of Antihist-1

Antihistamines (sedating type)

Mechanism of action of Antihist-1

Competitively blocks the effects of histamine at peripheral H1 receptor sites.

Indications of Antihist-1

  1. Relief of symptoms associated with perennial and seasonal allergic rhinitis; vasomotor rhinitis; allergic conjunctivitis; mild, uncomplicated urticaria and angioedema
  2. Amelioration of allergic reactions to blood or plasma
  3. Dermatographism
  4. Adjunctive therapy in anaphylactic reactions

Contraindications of Antihist-1

  1. Allergy to any antihistamines
  2. Narrow angle glaucoma

Adverse effects of Antihist-1

  • CNS: Sedation, sleepiness, dyscoordination, somnolence, headache, dizziness, nervousness
  • GI: Epigastric distress
  • CV: Palpitation, tachycardia, hypotension
  • Respiratory: Thickening of bronchial secretions
  • General: Weight gain
  • Other: Photosensitivity, rash, urticaria, angioedema

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