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Name: Azelastine

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Pregnancy Category C

Drug classes of Azelastine

Antihistamines

Mechanism of action of Azelastine

Competitively blocks the effects of histamine at peripheral H1 receptor sites; has sedative effects.

Indications of Azelastine

1. Nasal spray: Relief of symptoms associated with seasonal allergic rhinitis; sneezing, nasal pruritus, vasomotor rhinitis.
2. Ophthalmic: allergic conjunctivitis.

Contraindications of Azelastine

1. Allergy to any antihistamines
2. Narrow angle glaucoma
3. Bladder neck obstruction
4. Symptomatic prostatic hypertrophy
5. Asthmatic attack
6. Stenosing peptic ulcer
7. Pyloroduodenal obstruction
8. Not to be used in neonates (possible association with SIDS)

Adverse effects of Azelastine