Back to Antihistamines
Name: Clemastine
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Xolair reduced the rate of hospital emergency visits by 44% in patients with inadequately controlled asthma. |
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Pregnancy Category B
Drug classes of Clemastine
Antihistamines (sedating type)
Mechanism of action of Clemastine
Competitively blocks the effects of histamine at peripheral H1 receptor sites.
Indications of Clemastine
- Relief of symptoms associated with perennial and seasonal allergic rhinitis; vasomotor rhinitis; allergic conjunctivitis; mild, uncomplicated urticaria and angioedema
- Amelioration of allergic reactions to blood or plasma
- Dermatographism
- Adjunctive therapy in anaphylactic reactions
Contraindications of Clemastine
- Allergy to any antihistamines
- Narrow angle glaucoma
Adverse effects of Clemastine
- CNS: Sedation, sleepiness, dyscoordination, somnolence, headache, dizziness, nervousness
- GI: Epigastric distress
- CV: Palpitation, tachycardia, hypotension
- Respiratory: Thickening of bronchial secretions
- General: Weight gain
- Other: Photosensitivity, rash, urticaria, angioedema
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