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Date of last update: 10/17/2017.

Forum Name: Endocrinology Topics

Question: Lithium and hypothyroidism

 jtcssj - Mon Sep 20, 2004 9:50 pm

I have been taking Lithium for over a year and have noticed significant changes in my body. Some of them include; fatigue, severe indigestion, confusion, poor memory, irregular menstrual cycles, severe depression, and dermatitis. I take 1200 mg per day and nothing else and my lithium serum levels are stable. I’m concerned about hypothyroidism. Could you tell me your take on it? Thank You very much for your time. Tracy.
 Dr. Tamer Fouad - Tue Sep 21, 2004 1:57 am

User avatar Hello,

Lithium inhibits the secretion of T4 and T3 by poorly understood mechanisms. This may lead to hypothyroidism in 20-30% of cases. Lithium induced hypothyroidism usually responds well to replacement therapy and lithium therapy can continue with thyroxine.

I would advise you to consult your doctor and if on examination he finds that hypothyroidism is a possibility then he will request thyroid function tests which are the only way to tell if hypothyroidism exists or not.

Best regards,

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